Amazonia is home to more than half of the world's remaining tropical forests, playing a key role as reservoirs of carbon and biodiversity. However, whether at a slower or faster pace, continued deforestation causes forest fragmentation in this region. Thus, understanding the relationship between forest fragmentation and fire incidence and intensity in this region is critical. Here, we use MODIS Active Fire Product (MCD14ML, Collection 6) as a proxy of forest fire incidence and intensity (measured as Fire Radiative Power-FRP), and the Brazilian official Land-use and Land-cover Map to understand the relationship among deforestation, fragmentation, and forest fire on a deforestation frontier in the Brazilian Amazonia. Our results showed that forest fire incidence and intensity vary with levels of habitat loss and forest fragmentation. About 95% of active fires and the most intense ones (FRP > 500 megawatts) were found in the first kilometre from the edges in forest areas. Changes made in 2012 in the Brazilian main law regulating the conservation of forests within private properties reduced the obligation to recover illegally deforested areas, thus allowing for the maintenance of fragmented areas in the Brazilian Amazonia. Our results reinforce the need to guarantee low levels of fragmentation in the Brazilian Amazonia in order to avoid the degradation of its forests by fire and the related carbon emissions.Forests 2018, 9, 305 2 of 16 on access to credit, expansion of protected areas, and civil society interventions in the soy and beef supply chains [16]. Nonetheless, the deforestation rate increased markedly in 2015 and 2016 [15] (24% and 27% in relation to the previous year, respectively), raising concerns that the recent weakening of environmental-protection policies could be already reversing the Brazilian progress in reducing the Amazonian forest destruction.Whether at a slower or faster pace, continued deforestation cumulatively causes forest habitat loss, altering habitat configuration, such as the change in spatial arrangement of the remaining habitat through forest fragmentation. Metrics of habitat configuration, such as the number and mean size of forest patches and edge length covary with habitat amount. Understanding these relationships is important to correctly interpret the effects of habitat fragmentation on tropical forests [17]. Following Farhig (2003) [18], the mean patch size of remaining forests is expected to linearly decrease with the reduction in habitat amount, while both the number of patches and the total edge are expected to rise up to a certain threshold of habitat loss and then decrease with increasing deforestation.Forest edges resulting from landscape fragmentation are highly fire-prone due to increased dryness, higher fuel load compared to forest interior and proximity to ignition sources from adjacent management areas [19][20][21][22][23][24]. Fragmentation and its resulting edge effects may act synergistically with the ongoing large-scale changes in climate and fire regimes, threate...