Form‐fill‐seal methodology for controlled encapsulation of small silver particles in hyperbranched polyglycidol

Abstract

Production of polar hyperbranched polymers and encapsulation of small particles in the hyperbranched polymers is like ''forming'' pouches and then ''filling'' these pouches. Modification of the end-groups of the hyperbranched polymers with relative apolar groups is like ''sealing'' the pouches. In this article, we demonstrated that two methods depending on changed sequences, i.e., Form-Fill-Seal and Form-Seal-Fill methods resulted in different sized small particles with sizedepended properties. By using these approaches, small metal nano-particles can be encapsulated inside polar microzones of dendritic-star polymers taking advantage of the difference in partition coefficients instead of strong interactions between the dendritic polymers and ions. We used the methodology to produce small silver particles encapsulated in hyperbranched polyglycidol (HPG).The HPG was synthesized via anionic ring-opening multibranching polymerization of glycidol. The ''sealing'' process was fulfilled by polymerization of e-caprolactone initiated from the end groups of HPG. In the FormFill-Seal approach, Ag þ was filled inside HPG, and then was sealed before reduction to Ag; whereas the ''pouch'' of HPG was sealed at first, and then Ag þ was filled inside HPG by diffusion in the Form-Seal-Fill approach. Mainly nanometer-sized silver particles were formed by the Form-Fill-Seal approach, whereas silver clusters of several atoms were formed in the Form-Seal-Fill approach.

Aliphatic polyester polymer stars: synthesis, properties and applications in biomedicine and nanotechnology

“…As with lactide, we provide here the PCL dendritic stars employing hyperbranched cores that self-identify as having star-like characteristics. Derivatives of bMPA, 81,[201][202][203][204][205][206][207][208][209][210][211][212][213][214][215][216][217][218][219][220] PEG, 60,221,222 polyglycerols, 83,223,224 PAMAM, 77,[225][226][227][228] polyamines, 78,229 hyperbranched poly(hydroxyethylmethacry-late), 230 poly(ether)amides, 231,232 poly(ester)amides, 233 and PEIs. [234][235][236] Dendritic star polymer architectures with PCL date back to 1998.…”

General Avenue to Multifunctional Aqueous Nanocrystals Stabilized by Hyperbranched Polyglycerol

“…The binding of HPG-Au-Gly nanocrystals with DNA. To complex with DNA, the terminal amines on the HPG-Au-Gly nanocrystals were first protonated by adding a prescribed amount of Up to now, various topologies of functional polymers including linear polymers (e.g., polyvinylpyrrolidone (PVP), [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] poly(vinyl alcohol) (PVA), [16][17][18][19][20][21][22] poly(acrylic acid) (PAA), [23][24][25] polyacrylamide (PAM), 26,27 block polymer (BP), [28][29][30][31][32][33][34][35][36][37] and natural polymer (NP) [38][39][40][41] ), hyperbranched polymers (HPs) (e.g., terminated amphiphilic hyperbranched polyglycerol (AHPG), [42][43][44][45][46] hyperbranched polyethylenimine (HPEI), [47][48][49][50] hyperbranched poly(amido amine) (HPAMAM), [51]…”