Formation of a hard tissue barrier after pulp cappings in humans. A systematic review

Abstract

Insufficient evidence grade does not necessarily imply that there is no effect of a pulp capping procedure or that it should not be used. Rather, the insufficient evidence underpins the need for high-quality studies.

Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with Mineral Trioxide Aggregate: a randomized controlled trial¶

“…Microbes and their products interfere with the pulpal response to capping materials. Therefore, the relevance of this and other reported studies conducted on healthy human teeth may be clinically limited (Olsson et al 2006). It would be of long-term interest if direct pulp capping studies on human teeth using MTA are performed on carious teeth with vital pulps that might be exposed during therapeutic procedures and the pulpal response studied histologically.…”

“…During the past three decades a number of publications appeared on pulp capping in humans using Ca(OH) 2 , bonding agents and other materials, including mineral trioxide aggregate (MTA). The papers have been systematically reviewed (Olsson et al 2006) to evaluate available evidence on the formation of hard tissue barrier after pulp capping. In total 107 studies were identified of which only 21 met the selection criteria for evaluation.…”

Importance of the diagnosis in the pulpotomy of immature permanent teeth

“…Clinical examination, comprising caries excavation and observation of sensitivity on tissue removal, palpation of vestibules and pulp vitality tests should preceede the radiographic examination in the diagnosis of pulp alterations. Several materials have been used as pulp-capping agents in pulpotomized teeth, among which formocresol, calcium hydroxide, ferrous sulfate and more recently mineral trioxide aggregate (1,3,4,7,8). Some of these materials, like calcium hydroxide, are able to induce the formation of a hard-tissue tissue barrier (1,3,8).…”

Cytotoxicity of New Calcium Aluminate Cement (EndoBinder) Containing Different Radiopacifiers

“…Direct pulp capping (DPC) consists of applying a protective agent over the pulp when it is exposed, preserving and maintaining the vitality and function of this specialized connective tissue (1). Studies have shown that mineral trioxide aggregate (MTA) is one of the most used capping agents for application on exposed pulps, with which new cements must be tested and compared (2,3).…”