Formation of micelles of diblock and triblock copolymers in a selective solvent

Izzo, Dora; Marques, Carlos M.

doi:10.1021/ma00078a012

Cited by 56 publications

(62 citation statements)

References 3 publications

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“…50 -52 As toluene is a more selective solvent for PS, the PS blocks form the outer shell of the micelle preventing an energetically unfavorable contact of the PVP block with the solvent. 53 The polar PVP core can now be used to incorporate metal precursor salt into the micelle. This process shifts the thermodynamic equilibrium between free polymer chains and assembled micelles toward the latter and decreases the CMC at the same time.…”

Section: Block Copolymer Nanolithographymentioning

confidence: 99%

Micro‐ and Nanopatterning of Active Biomolecules and Cells

Aydin

Hirschfeld-Warneken

Louban

et al. 2012

Intelligent Surfaces in Biotechnology

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Section: Block Copolymer Nanolithographymentioning

confidence: 99%

Micro‐ and Nanopatterning of Active Biomolecules and Cells

Aydin

Hirschfeld-Warneken

Louban

et al. 2012

Intelligent Surfaces in Biotechnology

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“…The spherical micellar aggregates of amphiphilic macromolecules in water have been investigated to clarify their micellar properties such as critical micelle concentration (CMC), size, shape, aggregation number, and structural stability, which depend on the conditions of the solution and the nature of the amphiphilic species such as chemical structure and solvophobicity of the amphiphile. 19,20 Polymeric micelles, with their numerous advantages including considerable thermodynamic stability, formation of hydrophobic core, small size, and hydrophilic outershell designed to minimize the potential for favorable interaction with other components of the environment such as physiological fluids or organs, 21,22 have attracted great attention for applications in drug delivery systems. The release behavior of the drug from the micelles is affected by the nature of the drug (solubility, crystallinity, etc.…”

Section: Polymer Micellementioning

confidence: 99%

Preparation of polymeric self-assembly and its application to biomaterials

et al. 2003

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The self-assembly of polymers can lead to supramolecular systems and is related to the their functions of material and life sciences. In this article, self-assembly of Langmuir-Blodgett (LB) films, polymer micelles, and polymeric nanoparticles, and their biomedical applications are described. LB surfaces with a well-ordered and layered structure adhered more cells including platelet, hepatocyte, and fibroblast than the cast surfaces with microphase-separated domains. Extensive morphologic changes were observed in LB surface-adhered cells compared to the cast films. Amphiphilic block copolymers, consisting of poly(γ-benzyl L-glutamate) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) [or poly(N-isopropylacrylamide) (PNIPAAm)] as the hydrophilic one, can self-assemble in water to form nanoparticles presumed to be composed of the hydrophilic shell and hydrophobic core. The release characteristics of hydrophobic drugs from these polymeric nanoparticles were dependent on the drug loading contents and chain length of the hydrophobic part of the copolymers. Achiral hydrophobic merocyanine dyes (MDs) were self-assembled in copolymeric nanoparticles, which provided a chiral microenvironment as redshifted aggregates, and the circular dichroism (CD) of MD was induced in the self-assembled copolymeric nanoparticles.

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“…curve (-) generated using simultaneous differential equations [12]- [14] and eq. [27] with that (---) generated using eq.…”

Section: Inserting Eq [16] and Simplifying Givesmentioning

confidence: 99%

“…Donor fluorescence intensity decay data were generated using eqs. [12]- [14] and [27] by setting m = 10, k,, = 1.00 x lo4 (M-' s-'), k-,, = 10' (s-I), C ; = lo4 M, and ii = 100.…”

Section: Inserting Eq [16] and Simplifying Givesmentioning

confidence: 99%

“…Significant progress has been made M~l * M,,-l + U kt, in the theoretical (5)(6)(7)(8)(9)(10)(11)(12) and experimental (13)(14)(15)(16)(17)(18)(19) understanding of the equilibrium properties, such as the size and where k,, and k-, are the rate constants for chain incorporaaggregation number, of micelles. The study of micelle chain tion into and dissociation from a micelle, respectively.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chain exchange kinetics of diblock copolymer micelles studied by nonradiative energy transfer. 1. Experimental design and theory

Liu¹

1995

Can. J. Chem.

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A fluorescence experiment involving mixing donor-labeled micelles with acceptor-labeled unimers has been designed and a kinetic scheme for describing such an experiment has been proposed. An approximate analytical solution was found for the decrease in the donor fluorescence intensity at time t after sample mixing relative to that at time zero, I(t) [I(O). Treating the data of this decrease in donor fluorescence intensity as a function of time using the derived equation allows the simultaneous determination of the rate constant k,, for unimer incorporation into micelles and the quenching efficiency cp of donor fluorescence by an acceptor in a micelle.Key words: polymer micelles, dynamics, chain exchange, energy transfer.RCsumC : On a mis au point une expCrience de fluorescence impliquant le melange des micelles contenant un donneur marquC avec des unimkres accepteurs marquCs et on propose un schCma cinCtique pour dCcrire une telle expkrience. On a trouvC une solution analytique approximative pour expliquer la diminution de llintensitC de la fluorescence du donneur A un temps t. relatif au temps zCro, l(t)/1(0), du mClange de I'Cchantillon. Le traitement des donnCes relatives A la diminution de 1'intensitC de la fluorescence du donneur en fonction du temps en faisant appel ? i 1'Cquation dCrivCe permet de dtterminer simultanCment la constante de vitesse, k,,, pour l'incorporation de l'unimkre dans les micelles et pour I1efficacitC d'extinction, cp, de la fluorescence d'un donneur par un accepteur dans une micelle.Mots clis : micelles de polymkre, dynamique, Cchange de chaine, transfert d'Cnergie.[Traduit par la rCdaction]

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Formation of micelles of diblock and triblock copolymers in a selective solvent

Cited by 56 publications

References 3 publications

Micro‐ and Nanopatterning of Active Biomolecules and Cells

Micro‐ and Nanopatterning of Active Biomolecules and Cells

Preparation of polymeric self-assembly and its application to biomaterials

Chain exchange kinetics of diblock copolymer micelles studied by nonradiative energy transfer. 1. Experimental design and theory

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