Formation of thiazol-2(3H)-imines by reaction of α-amino acids, aroylisothiocyanates, and α-bromoketones in an ionic liquid

Reactivity and diverse synthetic applications of acyl isothiocyanates

“…90 Functionalized thiazol-2(3H)-imines 153 are obtained in excellent yields. The method is also advantageous because the ionic liquid can be recycled by extraction from the aqueous base.…”

A CMC-g-poly(AA-co-AMPS)/Fe3O4 hydrogel nanocomposite as a novel biopolymer-based catalyst in the synthesis of 1,4-dihydropyridines

“…3,[18][19][20][21] These are evaluated as valuable and efficient methods due to the time-saving, atom-economy, and environmentally friendly nature. [22][23][24][25][26] The Hantzsch reaction has been identied as one of the most widely used and effective multicomponent reactions for the synthesis of 1,4-dihydropyridine (1,4-DHP) derivatives. 1,4-DHP derivatives, as important nitrogen-containing heterocyclic compounds, displayed valuable pharmaceutical and biological activities.…”

Green synthesis of new thiouracilodepsipeptides in ionic liquid: One‐pot four‐component reaction of isocyanides

“…Other vital properties of RTILs including their density, viscosity, melting point, polarity, refractive index can be tuned by modifying the structures of their cation and anion components. As part of our current studies on the (IMCRs), [17][18][19][20][21] herein we report a one-pot four-component reaction to produce some thiouracilodepsipeptide derivatives (Scheme 1). [13] From this perspective, combining synthetic potentialities of MCRs with the dual properties of RTILs as solvents and promoters results in the emergence of promising strategies for the growth of costly ecocompatible organic synthesis procedures.…”