FORMULASI PASTA GIGI EKSTRAK DAUN SALAM (Syzygiumpolyanthawight) SEBAGAI PENGHAMBAT PERTUMBUHAN Streptococcus mutans

Saputri, Gusti Ayu Rai; Chusniasih, Dewi; Putri, Eka Ananda

doi:10.33024/jfm.v3i1.2998

Cited by 3 publications

(3 citation statements)

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“…Kontrol positif yang digunakan adalah pepsodent herbal memiliki nilai diameter zona hambat 4,71 mm yang termasuk kategori lemah. Hal ini berbeda dengan penelitian sebelumnya sediaan pasta gigi dengan perbedaan konsentrasi daun salam yang diujikan ke bakteri Streptococcus mutans dengan kontrol positif yang digunakan Pepsodent herbal menghasilkan nilai zona hambat sebesar 8,15 mm kategori sedang (Saputri et al, 2020). Ekstrak daun sirih konsentrasi 10% dengan nilai zona hambat 24,024 mm kategori sangat kuat menunjukkan sifat antibakteri terhadap bakteri Streptococcus mutans (Anas et al, 2018).…”

Section: Uji Antibakteriunclassified

Antibacterial Activity And Stability Test Of Bidara Leaf Extract Toothpaste (Ziziphus mauritiana Lam) Against The Growth Of Streptococcus Mutans

Nawangsari,

Oktavia,

Samodra

2023

metamorfosa

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Bidara leaf extract (BLE) with a concentration of 20% proven to inhibit the growth of Streptococcus mutans bacteria with an inhibitory zone of 12.00 mm. The content compounds in bidara leaves includes alkaloids, flavonoids, tannins and saponins. The purpose of this study was determine the physical properties, stability and antibacterial activity of toothpaste preparations with differences in the concentration of BLE, namely FI(15%), FII(20%) and FIII(25%). The extraction method used is remaceration with 70% ethanol solvent, while the antibacterial activity inhibition method uses slurry diffusion. Results valuation of physical properties of pH parameters FI(7.4±0.1); FII(7.1±0.1) and FIII(7.0±0.1), viscosity parameters FI(5,581.5±61.25); FII (5,801.9±9.60) and FIII (6,000.7±8.01). From results of the Onewayanova test, the difference extract concentration has a significant effect on pH and viscosity parameters (p-value<0.05). While the value of foam formation FI(7.4±0.1); FII(7.3±0.3) and FIII(7±0.1), from the results of Onewayanova test difference in extract concentration did not have a significant effect on the foam formation parameter (p-value>0.05). The results of stability T-test differences in the concentration of toothpaste extracts are stable on pH parameters, and FI on foam formation parameters due to sig.values (2-tailed<0.05). While the difference in toothpaste extract concentration is unstable in viscosity parameters and FII, FIII in foam formation parameters due to sig.values (2-tailed<0.05). In antibacterial testing, BLE toothpaste preparations all formulas can inhibit the growth of Streptococcus mutans bacteria with inhibitory zones FI(4.39±0.45cm), FII(5.44±0.49cm) and FIII(8.38±0.28cm). Based on these results, it can be concluded that FIII is the best formula with the largest inhibitory zone value.

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Section: Uji Antibakteriunclassified

Antibacterial Activity And Stability Test Of Bidara Leaf Extract Toothpaste (Ziziphus mauritiana Lam) Against The Growth Of Streptococcus Mutans

Nawangsari,

Oktavia,

Samodra

2023

metamorfosa

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“…Pasta gigi mengandung fluoride sebagai kandungan utama untuk mencegah kerusakan gigi, memperkuat gigi, memutihkan gigi, dan mencegah terjadinya karies gigi. Namun, fluoride tidak efektif dalam membunuh bakteri pada gigi, serta penggunaan yang berlebihan dapat menyebabkan kerentanan tulang, kerusakan gigi, risiko aborsi spontan, fluorosis enamel yang tidak dapat diperbaiki, penuaan dini, dan potensi karsinogenik [11]. Sehingga perlu dikembangkan pasta gigi yang sehat dengan penggunaan bahan alam sebagai alternatifnya guna mengurangi zat kimia.…”

Section: Hasil Dan Pembahasanunclassified

Aktivitas Antibakteri Ekstrak Cengkeh (Syzygium aromaticum) sebagai Sediaan Pasta Gigi

Gusti Ayu Surya Ciptha Dewi,

Ni Made Widi Astuti

2023

WSNF

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Karies gigi adalah penyakit yang dapat merusak struktur gigi akibat erosi dan degradasi enamel gigi. Karies gigi terjadi ketika sisa makanan dan bakteri dalam mulut berinteraksi dan membentuk asam yang akan merusak enamel gigi. Sehingga diperlukan senyawa yang memiliki aktivitas antibakteri untuk menghindari kerusakan enamel gigi. Bakteri utama yang menjadi penyebab karies gigi adalah Streptococcus mutans. Tanaman yang mempunyai aktivitas sebagai penghambat dalam pertumbuhan bakteri Streptococcus mutans adalah cengkeh (Syzygium aromaticum). Penulisan review artikel ini bertujuan untuk mengetahui kandungan cengkeh sebagai agen antibakteri serta potensinya dalam menghambat pertumbuhan bakteri penyebab karies gigi untuk dapat dimanfaatkan sebagai bahan aktif formulasi pasta gigi. Metode yang digunakan dalam artikel ini adalah literature review menggunakan penelusuran jurnal internasional dan jurnal nasional secara online yang dipublikasi dalam rentang 5 tahun terakhir yaitu tahun 2018-2023. Berdasarkan kajian literatur yang telah dilakukan, ekstrak cengkeh mengandung senyawa metabolit seperti alkaloid, flavonoid, terpenoid, dan fenolik yang berperan sebagai antibakteri terhadap bakteri Streptococcus mutans dengan zona hambat lemah hingga kuat. Kesimpulan yang diperoleh bahwa ekstrak cengkeh berpotensi dimanfaatkan sebagai antibakteri terhadap bakteri penyebab karies gigi pada sediaan pasta gigi, sehingga perlu dilakukan penelitian lebih lanjut mengenai formulasi serta efektivitas antibakteri terhadap sediaan pasta gigi dengan bahan aktif ekstrak cengkeh.

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“…The utilization of bay leaf in dentistry is still minimal. Previous researches on the use of bay leaf in dentistry are bay leaf ethanol extract as an antibacterial toothpaste (Saputri et al, 2020), bay leaf infusion as mouthwash, and denture cleanser (Sumono and Wulan, 2008). Ethanol extract of the bay leaf with a 15% concentration is effective as extrinsic stain removal toothpaste active agent (Annisa et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Potential Effect of Bay Leaf (Syzygium polyanthum [Wight] Walp.) Essential Oil for Herbal Toothpaste Active Agent

2022

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Bay leaf is a herbal plant containing essential oil with antioxidant activity. Antioxidant effects give bay leaf essential oil ability as a toothpaste active agent. This research aim is to evaluate the chemical composition and antioxidant activity of bay leaf essential oil to find out the potential as toothpaste active agents. Bay leaf used in this research was taken from Lendah, Kulon Progo in the evening. Steam-hydrodistillation is conducted and chemical composition is analyzed using the GC-MS method. The Antioxidant activity test is conducted with DPPH and FRAP methods. Toothpastes were formulated with three concentrations of bay leaf essential oil (0.125%, 0.25%, 0.5%). Stain prevention test using formulated toothpastes, no active agent toothpaste (negative control), and commercial toothpaste (positive control) was conducted on 20 bovine teeth to obtain the value of colour change (ΔE) before and after the experiment, then analysed using one-way ANOVA parametric test (CI 95%). The chemical composition of bay leaf essential oil detected using GC-MS showed 29 compounds. The highest percentages are cis-4-decenal (37.87%), Decanal (16.73%), and octanal (16.63%). IC50 value from DPPH and FRAP method are 2.079µg/mL and 3.277µg/mL. One-way ANOVA test showed there was an effect from bay leaf essential oil as stain prevention toothpaste active agent. Bay leaf essential oils toothpastes have no significant difference in ΔE value to positive control toothpaste. The conclusion of this research is bay leaf essential oil contains aldehyde compounds in high percentage which provides a very high antioxidant effect. Bay leaf essential oil is the potential to be used as a toothpaste active agent.

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FORMULASI PASTA GIGI EKSTRAK DAUN SALAM (Syzygiumpolyanthawight) SEBAGAI PENGHAMBAT PERTUMBUHAN Streptococcus mutans

Cited by 3 publications

References 0 publications

Antibacterial Activity And Stability Test Of Bidara Leaf Extract Toothpaste (Ziziphus mauritiana Lam) Against The Growth Of Streptococcus Mutans

Antibacterial Activity And Stability Test Of Bidara Leaf Extract Toothpaste (Ziziphus mauritiana Lam) Against The Growth Of Streptococcus Mutans

Aktivitas Antibakteri Ekstrak Cengkeh (Syzygium aromaticum) sebagai Sediaan Pasta Gigi

Potential Effect of Bay Leaf (Syzygium polyanthum [Wight] Walp.) Essential Oil for Herbal Toothpaste Active Agent

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