Formulation and Evaluation of Topical Linezolid Nanoemulsion for Open Incision Wound in Diabetic Animal Model

Haider, Faheem; Khan, Barkat Ali; Khan, Muhammad Khalid

doi:10.1208/s12249-022-02288-8

Cited by 14 publications

(2 citation statements)

References 14 publications

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“…The findings of the study by Faraji et al 16 showed that BC can be used as a safe natural medicine in the healing of episiotomy wounds. Today, various studies have been performed to evaluate the different chemical and plant compounds as nanoemulsion in wound healing, which have yielded significant results 55,56 . The result of this study also provided a new horizon for the use of BC plant as nanoparticles for wound healing in future studies.…”

Section: Discussionmentioning

confidence: 75%

Evaluation of antibacterial and wound‐healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study

Hasson

Jasim

Salman

et al. 2022

J of Cosmetic Dermatology

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Wounds are defined as the cellular and anatomical destruction of tissues that can be caused by chemical, physical, microbiological, thermal, or immunological damage, leading to skin rupture. 1 Wound healing is one of the most complex biological processes, with four overlapping phases: hemostasis, inflammation, proliferative, and maturation. These phases lead to the regeneration of new tissue. In burn injuries, blood coagulation occurs due to damaged capillaries, followed by inflammation. 2,3 The global cost of wound care averaged 2.8 billion dollars in 2014 and is expected to reach 3.5 billion dollars by 2021. 4 A 2018 analysis

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Section: Discussionmentioning

confidence: 75%

Evaluation of antibacterial and wound‐healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study

Hasson

Jasim

Salman

et al. 2022

J of Cosmetic Dermatology

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“…[20,21] For example, a topical nanoemulsion of linezolid has been shown to successfully deliver the drug to the target tissue and attenuate diabetic wounds. [22] However, the improper and indiscriminate uses of antibiotics have led to the evolution of strains that are extrinsically or intrinsically resistant (such as resistance caused by mutations and amplifications). The development of methicillin-resistant S. aureus (MRSA) as well as the evolution of extended-spectrum 𝛽-lactamase-resistant Escherichia coli has deteriorated public health.…”

Section: Introductionmentioning

confidence: 99%

Diverse Antibacterial Treatments beyond Antibiotics for Diabetic Foot Ulcer Therapy

Jing

et al. 2023

Adv Healthcare Materials

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Diabetic foot ulcer (DFU), a common complication of diabetes, has become a great burden to both patients and the society. The delayed wound closure of ulcer sites resulting from vascular damage and neutrophil dysfunction facilitates bacterial infection. Once drug resistance occurs or bacterial biofilm is formed, conventional therapy tends to fail and amputation is unavoidable. Therefore, effective antibacterial treatment beyond antibiotics is of utmost importance to accelerate the wound healing process and prevent amputation. Considering the complexity of multidrug resistance, biofilm formation, and special microenvironments (such as hyperglycemia, hypoxia, and abnormal pH value) at the infected site of DFU, several antibacterial agents and different mechanisms have been explored to achieve the desired outcome. The present review focuses on the recent progress of antibacterial treatments, including metal‐based medications, natural and synthesized antimicrobial peptides, antibacterial polymers, and sensitizer‐based therapy. This review provides a valuable reference for the innovation of antibacterial material design for DFU therapy.

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Self-nanoemulsifying drug delivery system for nebulization: fabrication and evaluation for systemic delivery of atorvastatin

Saeed,

Shah,

Fahad

et al. 2024

Naunyn-Schmiedeberg's Arch Pharmacol

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Formulation and Evaluation of Topical Linezolid Nanoemulsion for Open Incision Wound in Diabetic Animal Model

Cited by 14 publications

References 14 publications

Evaluation of antibacterial and wound‐healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study

Evaluation of antibacterial and wound‐healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study

Diverse Antibacterial Treatments beyond Antibiotics for Diabetic Foot Ulcer Therapy

Self-nanoemulsifying drug delivery system for nebulization: fabrication and evaluation for systemic delivery of atorvastatin

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