Formulation of electrically conducting microemulsion-based organogels

Kantaria, Shilpa; Rees, Gareth D.; Lawrence, M. Jayne

doi:10.1016/s0378-5173(02)00491-x

Cited by 39 publications

(19 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, the advent of microemulsion-based gels (which amalgamate the advantages of microemulsions and gels) has helped in improving the patient compli- ance of microemulsions [72][73][74] . Microemulsion-based gels are formulated by employing a suitable polymer that is capable of modifying the rheological behavior of microemulsions.…”

Section: Microemulsionsmentioning

confidence: 99%

“…However, it is essential to ensure that the polymer does not alter the desirable features of microemulsions. Several gelling agents have already been studied for their potential to form microemulsion-based gels [72][73][74] . Merits of microemulsion as topical delivery system: • Excellent thermodynamic stability that ensures its long shelf life.…”

Section: Microemulsionsmentioning

confidence: 99%

See 1 more Smart Citation

Novel Drug Delivery Systems: Potential in Improving Topical Delivery of Antiacne Agents

Date

Naik²,

Nagarsenker³

2005

Skin Pharmacol Physiol

107

View full text Add to dashboard Cite

Acne is the most common cutaneous disorder of multifactorial origin with a prevalence of 70–85% in adolescents. The majority of the acne sufferers exhibit mild to moderate acne initially, which progresses to the severe form in certain cases. Topical therapy is employed as first-line treatment in mild acne, whereas for moderate and severe acne, systemic therapy is required in addition to topical therapy. Currently, several topical agents are available that affect at least one of the main pathogenetic factors responsible for the development of acne. Although topical therapy has an important position in acne treatment, side effects associated with various topical antiacne agents and the undesirable physicochemical characteristics of certain important agents like tretinoin and benzoyl peroxide affect their utility and patient compliance. Novel drug delivery strategies can play a pivotal role in improving the topical delivery of antiacne agents by enhancing their dermal localization with a concomitant reduction in their side effects. The current review emphasizes the potential of various novel drug delivery strategies like liposomes, niosomes, aspasomes, microsponges, microemulsions, hydrogels and solid lipid nanoparticles in optimizing and enhancing the topical delivery of antiacne agents.

show abstract

Section: Microemulsionsmentioning

confidence: 99%

Section: Microemulsionsmentioning

confidence: 99%

Novel Drug Delivery Systems: Potential in Improving Topical Delivery of Antiacne Agents

Date

Naik²,

Nagarsenker³

2005

Skin Pharmacol Physiol

107

View full text Add to dashboard Cite

show abstract

“…The gelatin-containing microemulsion-based organogels (MBGs) are electroactive in nature, unlike most organogels, and may be used in iontophoretic delivery systems [73]. The iontophoretic delivery system which uses MBGs, loaded with bioactive agents, causes release of the bioactive agent at higher rates when compared to passive diffusion.…”

Section: Topical/transdermal Deliverymentioning

confidence: 99%

Organogels: Properties and Applications in Drug Delivery

Sahoo

Kumar

Bhattacharya

et al. 2011

Designed Monomers and Polymers

144

View full text Add to dashboard Cite

An organogel, a viscoelastic system, can be regarded as a semi-solid preparation which has an immobilized external apolar phase. The apolar phase is immobilized within spaces of the three-dimensional network structure formed due to the physical interactions amongst the self-assembling structures of compounds regarded as gelators. In general, organogels are thermodynamically stable in nature and have been explored as matrices for the delivery of bioactive agents. In the current paper, attempts have been made to understand the properties of organogels, various types of organogelators and some applications of the organogels in controlled delivery.

show abstract

“…Kantaria et al [108,109] reported on gelatin ME -based organogels (MBGs) as potential iontophoretic systems for the transdermal delivery of drugs. The microstructure of the proposed MBG was elucidated using small -angle neutron scattering where w/o ME droplets were entrapped in an extensive network of gelatin -water percolative channels.…”

Section: Transdermal Drug Deliverymentioning

confidence: 99%