Abstract:With the benefits of personalised learning environment in providing individual learning guidance and of guided-inquiry approach for driving students to inquire knowledge in procedural way, this study developed a personalised learning support system, which was based on conceptual learning problems, learning styles, and current understanding information, to provide guided-inquiry learning activities for individual students. The effects of the developed system on secondary school students Physics learning performance and learning attitudes were investigated. It was found that the students significantly outperformed on the developed system and their learning attitudes were positive. While, they showed the need of learning Physics in real context by basing on the developed system. In light of the aforesaid, this paper extends the proposed instructional strategy and addresses the application proposal by using the mobile device through authentic Physics laboratory activities. Keywords: mastery learning; mobile learning; personalised learning environment; guided inquiry; science education; online adaptive learning; interactive learning environment; learning style; conceptual learning suggestion; learning diagnostics.Reference to this paper should be made as follows: Wongwatkit, C., Panjaburee, P. and Srisawasdi, N. (2017) 'A proposal to develop a guidedinquiry mobile learning with a mastery learning mechanism for improving students' learning performance and attitudes in Physics', Int. J. Mobile Learning and Organisation, Vol. 11