“…To work in a single reactor, a viable way could be to work AGS in continuous-flow mode. In this case, the AGS–MBR process operates in a continuous flow and the aerobic granules come into direct contact with the membrane fibers ( Figure 2 c) [ 10 , 21 , 24 , 25 , 27 , 28 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ]. To date, the continuous-flow operation of AGS reactors is still a much-debated topic in the literature, and the main issue is represented by maintaining the stability conditions of granules in a configuration that does not normally include the alternation of the feast/famine phases [ 45 ].…”