Fouling with protein mixtures in microfiltration: BSA–lysozyme and BSA–pepsin

Palacio, Laura; Ho, Chao‐Hung; Prádanos, Pedro; Hernández, Antonio; Zydney, Andrew L.

doi:10.1016/s0376-7388(03)00143-1

Cited by 75 publications

(55 citation statements)

References 14 publications

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“…(112). The model has been extensively used to analyze the fouling behaviors in membrane filtration of a number of colloids under various operating conditions (Yuan et al, 2002;Ho and Zydney, 2002;Palacio et al, 2002Palacio et al, , 2003Taniguchi et al, 2003;Ye et al, 2005;Chandler and Zydney, 2006;Cogan and Chellam, 2009;Byun et al, 2011).…”

Section: Developments Of Concurrent Combined Modelmentioning

confidence: 99%

Developments of Blocking Filtration Model in Membrane Filtration

Iritani

Katagiri

2016

KONA

121

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Blocking filtration laws consist of four different filtration mechanisms: complete blocking, standard blocking, intermediate blocking, and cake filtration. Blocking filtration laws for describing both the pore blocking and cake formation have been extensively employed over the past several decades to evaluate the increase in filtration resistance with the progress of filtration in the field of classical particulate filtration. In recent years, blocking filtration laws become widely used also in membrane filtration such as microfiltration and ultrafiltration of colloids. This paper gives an overview of the developments of blocking filtration laws and equations under constant pressure and constant rate conditions reported for the filtrate flow of Newtonian and non-Newtonian fluids. The fouling index evaluating the degree of membrane fouling was examined on the basis of the blocking filtration equations. The blocking filtration laws were reexamined to extend the range of their application. Moreover, various combined models developed based on the blocking filtration laws were introduced for describing more rigorously the complicated filtration behaviors controlled by more than one mechanism which occurs successively or simultaneously.

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Section: Developments Of Concurrent Combined Modelmentioning

confidence: 99%

Developments of Blocking Filtration Model in Membrane Filtration

Iritani

Katagiri

2016

KONA

121

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“…Owing to the small particle size of BSA [38], most BSA molecules could pass through the UF membrane pores (average diameter of membrane pores: 40.3 75.6 nm). As a result, less serious membrane fouling was induced after filtration (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Bovine serum albumin (BSA, Electrophoresis Pure, Sinopharm Chemical Regent Co., Ltd, China) is typically used to represent protein [36,37]. It was dissolved in a solution of 0.15 M ionic strength phosphate buffered salt and was used within 8 h of preparation [38]. The isoelectric point (IEP) of BSA is at pH 4.7 and its typical molecular weight (MW) is 67 kDa [32].…”

Section: Chemical Reagents and Materialsmentioning

confidence: 99%

“…To support this hypothesis, three different low doses of alum salts, 1 mM, 7.5 mM and 20 mM, were used to investigate the filtration behavior after coagulating with BSA under different pH conditions. The initial solution pH value was set at 5.5, due to the fact that the IEP of BSA was at pH 4.7 [38] and a higher proportion of Al ml species was formed under this condition (Fig. 1).…”

Section: Correlation Between Membrane Flux and Solution Phmentioning

confidence: 99%

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Effect of aluminum speciation on ultrafiltration membrane fouling by low dose aluminum coagulation with bovine serum albumin (BSA)

Wang

et al. 2015

Journal of Membrane Science

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a b s t r a c tUp to now, many studies have focused on ultrafiltration (UF) membrane fouling when sweep flocculation is the main coagulation mechanism. However, there has been less focus on cases where charge neutralization is the main coagulation mechanism. Herein, UF membrane performance was investigated when bovine serum albumin (BSA) was coagulated with low dose aluminum chloride (AlCl 3 ) or polyaluminum chloride (PACl). For AlCl 3 or PACl, a large flux decline occurred at pH 5.5 and membrane fouling was steadily alleviated with increasing pH, resulting in a strong correlation between membrane flux and the corresponding solution pH. As pH rose, the proportions of Al ms (monomeric and small polymeric alum species) and Al u species (i.e., solid phase Al(OH) 3 ) gradually increased. A correlation was also observed between membrane flux and the proportions of Al ms and Al u . Compared with AlCl 3 , much more serious membrane fouling was induced when BSA was coagulated with PACl, owing to the lower proportions of Al ms and Al u species in the PACl system. For AlCl 3 , the potential fouling mechanism was pore constriction or blocking when the proportions of Al ms and Al u were lower than 62.3 75.1% (pH 6.0), followed by cake layer as the main fouling mechanism. For PACl, however, pore constriction or blocking occurred when the proportions of Al ms and Al u were lower than 35.473.2% (pH 6.5), and cake layer gradually became the main fouling mechanism.

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“…El modelo se ha aplicado con éxito en procesos de ultrafiltración de disoluciones de proteínas (Zydney y Ho, 2002;Palacio et al, 2003) y de materia orgánica natural (Yuan et al, 2002;Taniguchi et al, 2003). Los parámetros del modelo se calcularon empíricamente en todos los casos.…”

Section: Modelo Dinámico Que Combina El Bloqueo De Poros Y La Formaciunclassified

Modelado dinámico de procesos de ultrafiltración tangencial aplicados a la separación de macromoléculas.

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Fouling with protein mixtures in microfiltration: BSA–lysozyme and BSA–pepsin

Cited by 75 publications

References 14 publications

Developments of Blocking Filtration Model in Membrane Filtration

Developments of Blocking Filtration Model in Membrane Filtration

Effect of aluminum speciation on ultrafiltration membrane fouling by low dose aluminum coagulation with bovine serum albumin (BSA)

Modelado dinámico de procesos de ultrafiltración tangencial aplicados a la separación de macromoléculas.

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