Four years of clinical experience with an adverse reaction unit for dental biomaterials

Vamnes, Jan Sverre; Lygre, Gunvor Bentung; Grönningsæter, Arne Geir; Gjerdet, Nils Roar

doi:10.1111/j.0301-5661.2004.00148.x

Cited by 67 publications

(71 citation statements)

References 22 publications

(14 reference statements)

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“…86 Mercury from dental amalgam is associated with sensitization and intraoral lichenoid lesions in some cases. 87,88 Metallic mercury and mercury compounds were included among air pollutant compounds of concern due to toxicity and as respiratory tract irritants that may exacerbate asthma. 85 Selected results from analysis of mercury concentrations in smokeless tobacco and cigarette tobacco are summarized in Tables 1 and 2.…”

Section: Mercurymentioning

confidence: 99%

Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

2011

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Biochemically and pathologically, there is strong evidence for both atopic and nonatopic airway sensitization, hyperresponsiveness, and inflammation as a consequence of exposure to tobacco mainstream or sidestream smoke particulate. There is growing evidence for the relation between exposure to mainstream and sidestream smoke and diseases resulting from reactive oxidant challenge and inflammation directly as a consequence of the combined activity of neutrophils, macrophages, dendritic cells, eosinophils, basophils, as a humoral immunological consequence of sensitization, and that the metal components of the particulate play a role in adjuvant effects. As an end consequence, carcinogenicity is a known outcome of chronic inflammation.Smokeless tobacco has been evaluated by the IARC as a group 1 carcinogen. Of the many harmful constituents in smokeless tobacco, oral tissue metallothionein gradients suggest that metals contribute to the toxicity from smokeless tobacco use and possibly sensitization.This work reviews and examines work on probable contributions of toxic metals from tobacco and smoke to pathology observed as a consequence of smoking and the use of smokeless tobacco. Metals and metalloids in tobaccoThough exposure to substances from tobacco use is obviously a complex exposure, the carcinogens in tobacco smoke have been classified for health risk determinations into five major chemical classes. 1 Some of these have been carefully studied, contributing to a strong weight of evidence for associated health risks. 2 Toxic metals and metalloids constitute one of the more understudied major carcinogenic chemical classes in smokeless tobacco products and tobacco smoke. Eight of the top forty substances in the Fowles and Dybing table of cancer risk indices are metals or metalloid compounds. 1 In their table of non-cancer risk indices for individual chemical constituents of mainstream cigarette smoke based on a single cigarette per day, three of the top eight listed for respiratory effect health risk, cadmium, hexavalent chromium, and nickel, were metals. Another metalloid, silicon in the form of silicates, poses serious health risks by inhalation, but limited data is available, likely due to analytical difficulties.Metals and metalloids in smoke from biomass combustion including tobacco are generally considered to be present in ionic form, but may also occur in a gaseous elemental form, as is the case for mercury. 3 Whether a tobacco product is consumed by smoking or in a smokeless form, the exposure to toxic metals is directly related to the concentration in the tobacco leaf, assuming no metal containing additives are included during manufacture. [4][5][6] The soil (including any amendments to the soil such as sludge, fertilizers, or irrigation with

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Section: Mercurymentioning

confidence: 99%

Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

2011

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“…In the years 1999-2002 the Norwegian Dental Biomaterials Adverse Reaction Unit received an increasing number of reports of adverse reactions associated with composite materials, although these were still outnumbered by reactions to amalgam and other alloys , Vamnes et al 2004. Swedish data showed a similar tendency.…”

Section: Reports From Adverse Reaction Registry Unitsmentioning

confidence: 98%

Casting the runes

Sanderson

2012

Br Dent J

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“…World demand for palladium has been increased more than doubled in the past ten years 1 . The increasing demand for palladium in many (different) fields of technology led in the recent years to wide investigations on its toxicological effects [2][3][4][5][6] .…”

Section: Introductionmentioning

confidence: 99%

Synthesis of 5,6-Diphenyl-2,3-dihydro-1,2,4-triazine-3-thione as a New Reagent for Spectrophotometric Determination of Palladium

Tehrani

Tahmasebi²,

Souri³

et al. 2015

Chem Sci Trans

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Abstract:A new chromogenic reagent for the sensitive and selective determination of Pd 2+ ions in aqueous solution was synthesized. The reagent, 5,6-diphenyl-2,3-dihydro-1,2,4-triazine-3-thione, forms colored complexes with a few heavy metal ions. A 1:1 (M:L) yellowish orange colored complex of DPhDTT-Pd was formed in methanol. The molar absorptivity is 6.67×10 3 L mol -1 cm -1 . Bee's law was obeyed in the concentration range of 10-50 μg/mL at λ max 385 nm. The accuracy and precision of the method were evaluated on within-day and between-day basis; the relative error was ≤ 3.13 and the relative standard deviation was ≤3.96. The method was successfully applied to the synthetic samples and results compared with atomic absorption method. There was no significant difference between two methods (p>0.05).

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Four years of clinical experience with an adverse reaction unit for dental biomaterials

Cited by 67 publications

References 22 publications

Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

Casting the runes

Synthesis of 5,6-Diphenyl-2,3-dihydro-1,2,4-triazine-3-thione as a New Reagent for Spectrophotometric Determination of Palladium

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