1997
DOI: 10.1016/s0958-2592(97)90044-4
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Fractured talar beaks

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“…Patients who use cyclophosphamide for a prolonged period are at increased risk of developing malignancies in bone marrow, lymph nodes and especially bladder (Talar-Williams et al, 1996). The risk of bladder cancer is greater for patients who receive cyclophosphamide orally.…”
Section: Adverse Effects Of Cyclophosphamidementioning
confidence: 99%
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“…Patients who use cyclophosphamide for a prolonged period are at increased risk of developing malignancies in bone marrow, lymph nodes and especially bladder (Talar-Williams et al, 1996). The risk of bladder cancer is greater for patients who receive cyclophosphamide orally.…”
Section: Adverse Effects Of Cyclophosphamidementioning
confidence: 99%
“…Chronic use of cyclophosphamide may also cause bleeding from the bladder, the severity ranging from microscopic haematuria to haemorrhagic cystitis, which can be lifethreatening (Talar-Williams et al, 1996). The IV administration of cyclophosphamide combined with the protective organosulphur compound MESNA may reduce bladder toxicity (http://www.accessdata.fda.gov/drugsatfda_docs/label/ 2012/012141s089lbl.pdf accessed July 2013).…”
Section: Adverse Effects Of Cyclophosphamidementioning
confidence: 99%