Frailty decreases physical health domain of quality  of life in nursing home elderly

Handajani, Yvonne Suzy; Widjaja, Nelly Tina; Turana, Yuda

doi:10.18051/univmed.2015.v34.213-219

Cited by 3 publications

(3 citation statements)

References 17 publications

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“…Few studies have evaluated the relationship between frailty and Quality of life among general aged care home residents [22,23,24,25,26]. There exists no study focusing on a target population of aged care home residents taking CNS medications and reporting the relationship between frailty and medication appropriateness from a Malaysian perspective.…”

Section: Introductionmentioning

confidence: 99%

An Evaluation of the Central Nervous System Medication Use and Frailty among Residents of Aged Care Homes in Malaysia

et al. 2017

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Background/Aims: Old age and institutionalization in care homes are associated with increased use of risk medications affecting the central nervous system (CNS). This study evaluated medication utilization and appropriateness; and assessed frailty among residents of Malaysian aged care homes. Methods: The subjects of this study included 202 elderly (≥65 years) residents of 17 aged care homes in suburban peninsular Malaysia. Frailty was measured using the Groningen Frailty Indicator (GFI) score and independence in daily living was measured as KATZ activity of daily living score. Medication appropriateness was assessed using the Medication Appropriateness Index (MAI) and 2015 Beers' criteria for Potentially Inappropriate Medication (PIM). Results: CNS medications constituted about 16% of the total, with an average of 0.8 ± 1.1 medications per resident, which reduced to 0.5 ± 0.8 medications after 3 months. Frailty (154/202) and polypharmacy (90/202) were highly prevalent in study subjects.Subjects on CNS medications had significantly higher GFI score (7.1 vs. 5.9; p = 0.031), polypharmacy (57.8 vs. 35.3%; p = 0.002), number of PIMs (0.9 vs. 0.2; p = 0.001), and mean summed MAI score (3.6 vs. 2.6; p = 0.015) than subjects not on CNS medications. Medication number was also significantly correlated with GFI (r = 0.194; p = 0.006) and KATZ (r = 0.141; p = 0.046) scores. Conclusion: Frailty and polypharmacy were highly prevalent among aged care home subjects taking CNS medications. These findings support the notion that periodic regular medication review should improve the overall use of medications in elderly patients.

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Section: Introductionmentioning

confidence: 99%

An Evaluation of the Central Nervous System Medication Use and Frailty among Residents of Aged Care Homes in Malaysia

et al. 2017

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“…The sample size was calculated using planned proportion at a 95% confidence level to achieve a 5% margin of error, with previous frailty prevalence in Indonesia of 52.2%. 6 After obtaining permission from the head of home care and written informed consent signed by the respondents, the respondents were recruited. Respondents with physical and mental limitations were excluded.…”

Section: Methodsmentioning

confidence: 99%

“…4 A systematic review reported the prevalence of frailty and pre-frail in the community of 10.7% and 41.6%, respectively 5 whereas a study in Indonesia reported the prevalence of frailty was 52.2%. 6 Frailty increases the risk of premature death, falls, fractures, dementia which impair quality of life therefore, increasing health care cost. 7 A study in Germany has shown a relationship between an increase in the frailty index and an increase in health care costs.…”

Section: Introductionmentioning

confidence: 99%

Low Bone Mineral Density, Sedentary Lifestyle, and Depression as Risk Factors for Frailty Syndrome at a Home Care Facility in West Jakarta, Indonesia

Handajani

Subagya

Widjaja

2023

AMJ

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Background: The life expectancy in Indonesia is increasing. The rising number of the elderly people plays a vital role for a country to achieve development success. However, it has many consequences in the health sector, including a frailty syndrome. This study aimed to explore the association between frailty and related factors.Methods: This cross-sectional study was conducted at a home care facility in West Jakarta between September and October 2019, using a simple random sampling method. Data were analyzed using the chi-square test and multivariate logistic regression. The inclusion criteria were members of the home care aged ≥60 years and had signed a written informed consent.Results: In total, 97 respondents were included. Female gender and bone mineral density (BMD) were associated with frailty syndrome (p=0.018 and p=0.05, respectively). Multivariate logistic regression analysis showed the odds ratio of frailty for the female gender (OR= 3.319; 95% CI 1.045–10.543), low bone mineral density (OR= 4.939; 95% CI 1.516–16.090), depression (OR= 7.622; 95% CI 1.246 – 46.621), and low physical activity (OR = 3.639; 95% CI 1.096 – 12.079).Conclusions: There is a relationship between female gender and bone mineral density with frailty syndrome with the risk factors for frailty syndrome in this study are female gender, low bone mineral density, depression, and low physical activity.

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Prevalence of frailty in Indonesia: a systematic review and meta-analysis

Pradana,

Chiu,

Lin

et al. 2023

BMC Geriatr

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Background Frailty increases the risks of hospitalization, injury, fall, psychological disorders, and death in older adults. Accurate estimation of the prevalence of frailty is crucial for promoting health in these individuals. Therefore, this study was conducted to estimate the prevalence of frailty and prefrailty in older adults residing in Indonesia. Methods In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, six electronic databases were searched (without any language restriction) for relevant articles from inception to February 2023. Studies on the prevalence of frailty and prefrailty in older adults (age ≥ 60 years) residing in Indonesia were included in the analysis. A random-effects model was selected a priori because of the expected high degree of heterogeneity in the study, followed by sensitivity analysis, subgroup analysis, and meta-regression. The protocol of this review study was registered in the PROSPERO database (CRD42022381132). Results A total of 79 studies were identified, of which 20 were finally included in the analysis. The pooled prevalence of frailty and prefrailty in older adults in Indonesia was 26.8% and 55.5%, respectively. The pooled prevalence of frailty and prefrailty was 37.9% and 44.8% in nursing homes, 26.3% and 61.4% in hospitals, and 21.1% and 59.6% in community settings, respectively. Furthermore, the pooled prevalence of frailty and prefrailty was 21.6% and 64.3%, 18.7% and 62%, and 27.8% and 59.8% in studies using the Frailty Index-40, FRAIL, and Fried Frailty Phenotype questionnaires, respectively. However, the parameters did not vary significantly across measurement tools or study settings. Publication bias was not detected while the year of data collection influenced the heterogeneity between the studies. Conclusions To the best of our knowledge, this study is the first meta-analysis to report the prevalence of frailty and prefrailty in older adults residing in Indonesia. The gradual increase in the number of older adults with frailty or prefrailty in Indonesia is concerning. Therefore, the government, private sectors, health-care professionals, and the community must jointly design effective strategies and policies to address this problem.

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Frailty decreases physical health domain of quality of life in nursing home elderly

Cited by 3 publications

References 17 publications

An Evaluation of the Central Nervous System Medication Use and Frailty among Residents of Aged Care Homes in Malaysia

An Evaluation of the Central Nervous System Medication Use and Frailty among Residents of Aged Care Homes in Malaysia

Low Bone Mineral Density, Sedentary Lifestyle, and Depression as Risk Factors for Frailty Syndrome at a Home Care Facility in West Jakarta, Indonesia

Prevalence of frailty in Indonesia: a systematic review and meta-analysis

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