Frailty is associated with hospital readmission in geriatric patients: a prognostic study

Gregersen, Merete; Hansen, Troels Kjærskov; Jørgensen, Bodil B; Damsgaard, Else Marie

doi:10.1007/s41999-020-00335-w

Cited by 33 publications

(28 citation statements)

References 33 publications

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“…Frail older adults showed increased risk for 90-day hospital readmission and the need for more social support. These findings were supported in previous studies that report that frail patients have more risk for adverse outcomes compared to robust patients [6,9,10]. Results related to 30-day readmissions corroborate previous studies [9,11]; the majority of the studies examined only the 30 day hospital readmission.…”

Section: Discussionsupporting

confidence: 88%

The Role of Frailty in Predicting 3 and 6 Months Functional Decline in Hospitalized Older Adults: Findings from a Secondary Analysis

Tavares

Sá‐Couto

Reis

et al. 2021

IJERPH

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Frailty represents one of the most relevant geriatric syndromes in the 21st century and is a predictor of adverse outcomes in hospitalized older adult, such as, functional decline (FD). This study aimed to examine if frailty, evaluated with the Frailty Index (FI), can predict FD during and after hospitalization (3 and 6 months). Secondary data analysis of a prospective cohort study of 101 hospitalized older adults was performed. The primary outcome was FD at discharge, 3 and 6 months. The FI was created from an original database using 40 health deficits. Functional decline models for each time-point were examined using a binary logistic regression. The prevalence of frailty was 57.4% with an average score of 0.25 (±0.11). Frail patients had significant and higher values for functional decline and social support for all time periods and more hospital readmission in the 3 month period. Multivariable regression analysis showed that FI was a predictor of functional decline at discharge (OR = 1.07, 95% CI = 1.02–1.14) and 3-month (OR = 1.05, 95% CI = 1.01–1.09) but not 6-month (OR = 1.03, 95% CI = 0.99–1.09) follow-up. Findings suggest that frailty at admission of hospitalized older adults can predict functional decline at discharge and 3 months post-discharge.

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Section: Discussionsupporting

confidence: 88%

The Role of Frailty in Predicting 3 and 6 Months Functional Decline in Hospitalized Older Adults: Findings from a Secondary Analysis

Tavares

Sá‐Couto

Reis

et al. 2021

IJERPH

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“…Our study adds to earlier studies by focusing on a broad range of geriatric domains and their accumulation in an outpatient geriatric population. To date, available literature focused mainly on the association of separate geriatric domains with mortality in specific patient categories, for example, oncology, renal or heart failure patients [12,13,15], hospitalized geriatric patients [10,11,14], or solely on individual components [2,[31][32][33], with inconsistent findings. As a result, knowledge on the relation between a CGA, its geriatric domains and mortality in an outpatient geriatric population has remained sparse.…”

Section: Discussion/conclusionmentioning

confidence: 99%

“…Previous research has shown the value of separate geriatric domains in predicting adverse health outcomes in hospitalized patients or in disease-specific populations, such as oncology or heart failure populations [10][11][12][13][14][15]. To the best of our knowledge and somewhat surprising, however, the relation between different geriatric domain deficits and mortality in older patients referred to an outpatient geriatric clinic has not been studied.…”

Section: Introductionmentioning

confidence: 99%

Mortality Risk and Its Association with Geriatric Domain Deficits in Older Outpatients: The Amsterdam Ageing Cohort

et al. 2021

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Introduction: In older patients, life expectancy is determined by a complex interaction of multiple geriatric domains. A comprehensive geriatric assessment (CGA) captures different geriatric domains. Yet, if and how components of the CGA are related to mortality in an outpatient geriatric setting is unknown. In the Amsterdam Ageing Cohort, we therefore studied distribution and accumulation of geriatric domain deficits in relation to mortality. Methods: All patients received a CGA as part of standard care, independent of referral reason. We summarized deficits on the CGA, using predefined cutoffs, in 5 geriatric domains: somatic, mental, nutritional, physical, and social domain. Information on mortality was obtained from the Dutch municipal register. We used age- and sex-adjusted Cox proportional hazards analyses to relate the separate domains and accumulation of impaired domains to overall mortality. Results: From the 1,055 geriatric outpatients (53% female; age 79 ± 7 years), 172 patients (16%) had died after 1.7 ± 1.1 years. In 626 patients (59%), 3 or more domains were impaired. All domains were independently associated with mortality, with the highest hazard for the somatic domain (HR 3.7 [1.7–8.0]) and the lowest hazard for the mental domain (HR 1.5 [1.1–12.0]). In addition, accumulation of impaired domains showed a gradually increased mortality risk, ranging from HR 2.2 (0.8–6.1) for 2 domains to HR 9.6 (3.7–24.7) for all 5 domains impaired. Conclusions: This study provides evidence that impairment in multiple geriatric domains is highly prevalent and independently and cumulatively associated with mortality in an outpatient geriatric setting.

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“…We read with great interest, the article "Frailty Is Associated With Hospital Readmission in Geriatric Patients: A Prognostic Study" [1]. The authors assessed frailty using the Multidimensional Prognostic Index (MPI) in geriatric patients who were acutely admitted.…”

Section: Dear Editormentioning

confidence: 99%

Comments to “Frailty is associated with hospital readmission in geriatric patients: a prognostic study”

et al. 2020

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Frailty is associated with hospital readmission in geriatric patients: a prognostic study

Cited by 33 publications

References 33 publications

The Role of Frailty in Predicting 3 and 6 Months Functional Decline in Hospitalized Older Adults: Findings from a Secondary Analysis

The Role of Frailty in Predicting 3 and 6 Months Functional Decline in Hospitalized Older Adults: Findings from a Secondary Analysis

Mortality Risk and Its Association with Geriatric Domain Deficits in Older Outpatients: The Amsterdam Ageing Cohort

Comments to “Frailty is associated with hospital readmission in geriatric patients: a prognostic study”

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