Frameless Stereotactic Lesion Contour-guided Surgery Using a Computer-navigated Microscope

High Diagnostic Accuracy of Cytologic Smears of Central Nervous System Tumors

“…Even stereotactically directed navigation systems providing intraoperative radiologic resection guidance cannot solve the problem of defining tumor margins in radiologically well delineated tumor areas, because shift phenomena during resection of large tumor volumes occur. [25][26][27] Since the extent of resection determines survival in…”

Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study

“…Extent of resection was rated as biopsy (stereotactic or frameless stereotactic using Nashold needle and burr hole), partial resection (residual tumour visible on postsurgical contrastenhanced magnetic resonance imaging (MRI)) or macroscopically complete resection (no residual tumour visible on postoperative contrast enhanced MRI). All procedures were augmented by a surgical navigation system [19,20], additionally by fl uorescence guided resection using 5-aminolevulinic acid (5-ALA) since May 2009 [22]. Altogether, 16 patients received biopsy only (deep seated, eloquent, non-resectable tumours), 18 patients received partial resection (to preserve eloquent brain areas) and 14 patients had GTR.…”

Risk Reduction in Dominant Temporal Lobe Epilepsy Surgery Combining fMRI/DTI Maps, Neuronavigation and Intraoperative 1.5-Tesla MRI

“…Risk areas as well as the lesion volumes were segmented and displayed in different colors on the scans and projected through the microscope onto the intraoperative operating field. Thus, the operation microscope (Pentero, Zeiss, Oberkochen, Germany) was used to integrate the functional risk maps for targeting and guiding the resection of the lesions intraoperatively using standard microsurgical techniques as described earlier [25]. During lesion resection, the ocular displayed risk areas were respected and lesioning of risk brain areas avoided, especially concerning speech- and memory-relevant cortical areas and the visual tract.…”