Frecuencia del síndrome de Down en Asturias y tendencia temporal, 1990–2004

Tenreiro, Carmen Mosquera; Hevia, Fernando Ariza; Dehli, Cristina Rodríguez; Toral, Joaquín Fernández; López, Enrique García; Galán, Isolina Riaño

doi:10.1016/j.medcli.2008.10.052

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…This topic has received little attention in persons with Down syndrome due to we did not find literature about, but several studies have discussed the importance of footwear in other population, emphasizing that a poorly fitting shoe was linked to increased impairment and foot pain [ 38 , 45 , 46 , 47 , 48 , 49 ].…”

Section: Discussionmentioning

confidence: 99%

“…The sample size was calculated with the software from Unidad de Epidemiología Clínica y Bioestadística, Complexo Hospitalario Universitario de A Coruña, Universidade da Coruña (available at ) [ 37 ]. Considering the prevalence of 29.1 cases of Down syndrome per 10,000 persons in the northwestern region of Spain and the total population of 69,452 persons (available on ) in the city of Ferrol [ 38 ], the sample size calculation for an α level of 5% (confidence interval, α-1 = 95%), an error β of 20% with a power analysis of 80%, a proportion of 5% and a precision of ±7%, produced a minimum of n = 37 cases. Furthermore, assuming information loss of 15%, at least n = 44 cases must be studied.…”

Section: Methodsmentioning

confidence: 99%

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The Relationship between Shoe Fitting and Foot Health of Persons with Down Syndrome: A Case Control Study

Calvo‐Lobo

García

Iglesias

et al. 2018

IJERPH

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Background: Down syndrome is the most common chromosomal abnormality and a cause of intellectual disability. It is also associated with orthopaedic and musculoskeletal problems of the locomotive apparatus, especially of the feet. These problems are believed to have a harmful effect on health, social functioning, and mobility. In addition, these persons generally don’t have access to podiatric health services, even when their foot problems are well known, because of limited access to healthcare facilities. The goal of our research was to evaluate and compare the foot health status of study participants with and without Down syndrome and to determine whether inadequate footwear is being used with normalized reference values. Methods: A total of 105 participants with and without Down syndrome, with a mean age of 35.71 (SD = 12.93) years, were enrolled in the study. They self-reported demographic data and their clinical characteristic data were recorded. Measurements of their foot and shoe fitting were taken at all stages of the research process. Ninety-two percent of the participants with Down syndrome had foot problems. Results: Only 12 (24%) participants with Down syndrome used bilateral shoes that met the requirements of their feet compared to their controls (50 participants, 90.9% for the right foot; 46 participants, 83.6% for the left foot). Participants with Down syndrome presented statistically significant differences with respect to controls and wore incorrectly sized shoe. Conclusions: Evaluation of foot length and width may prevent development of foot deformities, as well as to improve general health.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

The Relationship between Shoe Fitting and Foot Health of Persons with Down Syndrome: A Case Control Study

Calvo‐Lobo

García

Iglesias

et al. 2018

IJERPH

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“…Los individuos con sı ´ndrome de Down (SD) tienen una mayor incidencia de patologı ´as endocrinolo ´gicas que la poblacio ´n general. Dejando aparte el hipocrecimiento y la tendencia al sobrepeso/ obesidad, cuya prevalencia en el SD es tan alta que entran a formar parte de la descripcio ´n clı ´nica cla ´sica del sı ´ndrome, las alteraciones tiroideas, especialmente el hipotiroidismo y, en menor medida, la diabetes mellitus tipo 1 (DM1), constituyen las patologı ´as endocrinolo ´gicas ma ´s frecuentes 1 .…”

Section: Introduccio ´Nunclassified

Alteraciones endocrinológicas en 1.105 niños y adolescentes con síndrome de Down

et al. 2011

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How valid are the rates of Down syndrome internationally? Findings from the International Clearinghouse for Birth Defects Surveillance and Research

Leoncini¹,

Botto

Cocchi

et al. 2010

American J of Med Genetics Pt A

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Rates of Down syndrome (DS) show considerable international variation, but a systematic assessment of this variation is lacking. The goal of this study was to develop and test a method to assess the validity of DS rates in surveillance programs, as an indicator of quality of ascertainment. The proposed method compares the observed number of cases with DS (livebirths plus elective pregnancy terminations, adjusted for spontaneous fetal losses that would have occurred if the pregnancy had been allowed to continue) in each single year of maternal age, with the expected number of cases based on the best-published data on rates by year of maternal age. To test this method we used data from birth years 2000 to 2005 from 32 surveillance programs of the International Clearinghouse for Birth Defects Surveillance and Research. We computed the adjusted observed versus expected ratio (aOE) of DS birth prevalence among women 25-44 years old. The aOE ratio was close to unity in 13 programs (the 95% confidence interval included 1), above 1 in 2 programs and below 1 in 18 programs (P < 0.05). These findings suggest that DS rates internationally can be evaluated simply and systematically, and underscores how adjusting for spontaneous fetal loss is crucial and feasible. The aOE ratio can help better interpret and compare the reported rates, measure the degree of under- or over-registration, and promote quality improvement in surveillance programs that will ultimately provide better data for research, service planning, and public health programs.

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Frecuencia del síndrome de Down en Asturias y tendencia temporal, 1990–2004

Cited by 4 publications

References 7 publications

The Relationship between Shoe Fitting and Foot Health of Persons with Down Syndrome: A Case Control Study

The Relationship between Shoe Fitting and Foot Health of Persons with Down Syndrome: A Case Control Study

Alteraciones endocrinológicas en 1.105 niños y adolescentes con síndrome de Down

How valid are the rates of Down syndrome internationally? Findings from the International Clearinghouse for Birth Defects Surveillance and Research

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