Frequency of hypocalcemia and indirect hyperbilirubinemia in preterm babies remain admitted in Independent University Hospital.

Abstract

ABSTRACT… Premature birth and low-birth weight are major causes of neonatal mortality, occurrence is 29%. Complications of prematurity and its risk factors are comparatively lesser in late preterm babies. Preterm babies are at higher risk of development of Bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis, retinopathy of prematurity, patent ductus arteriosus sepsis, hypothermia, hypoglycemia, hypocalcaemia, and hyperbilirubinemia. No recent and current reliable data is available regarding frequency of hyperbilirubinemia and metabolic abnormalities in very preterm babies. Early detection of hyper-bilirubinemia, hypoglycemia and hypocalcaemia can help in better management and decrease neonatal morbidity and mortality. Objectives: To determine the frequency of hyperbilirubinemia and metabolic abnormalities in very preterm babies. Study Design: Cross sectional study. Setting: Methods: 120 very preterm singleton babies born between 28-34 weeks gestation, without lethal congenital anomalies and birth weight > 500 gram presenting in neonatal emergency within first 24 hours of birth were included. Neonates born to mothers with diabetes mellitus, addiction, renal failure, hemoglubinopathies, Rh negative blood group along with neonates with toxemia, congenital pneumonia, congenital malformation, or any genetic syndrome were excluded. Results: Mean gestational age was 31±1.4weeks. Male patients were dominant (52%) than the females (48%). Hyperbilirubinemia, hypoglycemia and hypocalcemia was present in 68(57%), 27(22.5%) and 23(19%) patients respectively. Conclusion: Hyperbilirubinemia and metabolic abnormalities are common in very preterm babies and by knowing the magnitude of these problems early preventive measure can be acquired to reduce the neonatal mortality and morbidity Valencil schuor et al 20 conducted a study showing that more than 15% of preterm having hyperlirubinemia 28% preterm born through c-section and 16% born through vaginal delivery having jaundice.My study showed that hyperbilirubinemia, hypoglycemia and hypocalcaemia was 65, 27 and 23 babies common in small of gestational age preterm. CONCLUSIONHyperbilirubinemia and metabolic abnormalities like hypoglycemia and hypocalcemia are common problems in very preterm babies. The results of my study give the local burden of these complications that can be helpful in highlighting the importance of screening of such conditions so that special attention could be given to these babies for reduction of neonatal mortality and morbidity. Copyright© 01 July, 2019.

Comparison of Serum Calcium Levels Among Extremely Preterm and Severly Preterm Neonates at a Peripheral Military Hospital

“…Many of them who survive experience chronic health disorders, the most frequent being cerebral palsy, impaired vision and hearing abnormalities 4 . Bajwa et al 5 , concluded that hyper-bilirubinemia and other metabolic anomalies like hypocalcaemia and hypoglycemia were very frequent in preterm infants, thus requiring timely management to prevent any loss of life. Preterm birth rates continue to rise all over the world, partially owing to increased rates of multiple pregnancies, as the rate of preterm birth is almost 40-60% in multiple pregnancies whereas in single pregnancies it is only 5-10% 6 .…”