From disease to noninvasive intracranial monitoring

Abstract

Professor Sérgio Mascarenhas was a Brazilian researcher with a vast legacy. His work paved the way for new research possibilities by consolidating the use of innovation and transdisciplinary science. In Medicine, he proposed changes to what had previously been well-accepted concepts, and his contributions have influenced medical practices. Although many authors consider intracranial pressure (ICP) as an unrivaled variable for monitoring and diagnosis of many diseases, its clinical applicability is still the subject of debate in the literature because of the difficulty in standardizing protocols. Mascarenhas's research and the creation of a device for noninvasive monitoring of intracranial compliance are discussed and are shown to have led to the creation of Brain4care, a start-up, and a new perspective on the debate on ICP monitoring.

Astrocytoma Mimicking Herpetic Meningoencephalitis: The Role of Non-Invasive Multimodal Monitoring in Neurointensivism

“…Innovative imaging modalities may provide hints for a differential diagnosis, while non-invasive methods may enable continuous monitoring of intracranial pressure to guide therapeutic actions. This case report describes the initial presentation of meningoencephalitis mimicking an astrocytoma in the central nervous system and the importance of a multimodal approach using non-invasive techniques to monitor ICH [10,11] and improve patient outcomes. Multimodal non-invasive techniques for monitoring ICH encompass a diverse array of methods (ultrasound, skull strain sensors) designed to assess elevated intracranial pressure (ICP) without the need for placement of an intraventricular catheter (gold standard) [12].…”

Métodos não invasivos para monitorização da pressão intracraniana: uma revisão atual

“…(FOLCHINI CM, et al, 2022).Para realizar o monitoramento da PIC através do Brain4care, é colocada uma faixa acoplada a um extensômetro mecânico ao redor dos ossos cranianos, geralmente na região parietal, lateralmente à sutura sagital, podendo também ser utilizado em outros ossos, como o occipital (PARAGUASSU G, et al, 2021). Esse dispositivo age como um sensor que detecta deformações micrométricas dos ossos cranianos, com sensibilidade para movimentos menores que 0,2 micrômetros (BRASIL S, et al, 2021), que irá filtrar, amplificar e digitalizar o sinal captado pelo sensor e enviá-lo para um computador.…”