From Gene Transfer to Risk Assessment: Experiences with Genetic Variability in Baculoviruses and New Approaches to Analyse the Reaction of Microbial Communities to Stress Factors

Backhaus, Horst; Nickel, Antje; Fritsch, Eva; Huber, Jürg; Wendt‐Potthoff, Katrin; Engelen, Bert; Felske, Andreas; Nübel, Ulrich; Jehle, Johannes A.

doi:10.1007/978-3-642-61460-6_4

Cited by 3 publications

(2 citation statements)

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“…Recombinational events in the genome during integration might result in rearrangements of genes and changed gene expression patterns not present in either parent (42). Greene and Allison (43) reported that a viral gene inserted into a plant could recombine with infecting viruses to create hybrids with new properties.…”

Section: Recombinationmentioning

confidence: 99%

“…Consequently, small scale releases must include thorough characterizations of release areas as well as surrounding habitats. In addition, information about how different climatic and environmental conditions may affect persistence and dispersal properties are needed, with the purpose to reduce the GMOs ability to invade or interact with other ecosystems (42,62).…”

Section: Microb Ecol Health Dis Downloaded From Informahealthcarecommentioning

confidence: 99%

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The Precautionary Principle Applied to Deliberate Release of Genetically Modified Organisms (GMOs)

Myhr

1999

Microbial Ecology in Health and Disease

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Deliberate release of genetically modified organisms (GMOs) may contribute to sustainable development, world food supplies and economic prosperity. On the other hand, environmental release may initiate serious, irreversible ecological damage. In this article we discuss the scientific basis for regulation of GMO use, and to which extent present risk assessment procedures provide means to predict and reduce potential ecological hazards. Potential hazards related to gene transfer from GMOs to indigenous organisms and prospects of secondary ecological effects are given special attention. It is important to recognize that possible adverse ecological effects may have impact on other processes affecting human and animal welfare. A major conclusion is that the present state of scientific knowledge is inadequate for reliable ecological risk assessment. The basic information with regard to mechanisms governing the environmental interactions of GMOs is insufficient. The ecosystems are too complex, and our understanding of them too fragmentary. Furthermore, currently available methods to monitor short and long-term ecological consequences of GMO release are non-existent or unreliable. Finally, the socio -economic and biodiversity aspects of GMO usage are ambiguous, and often unpredictable, based on the present state of knowledge. Hence, applying the precautionary principle should be an important basis for initiation of risk-associated research as well as for elaboration of more satisfactory risk assessment methods and procedures.

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Section: Recombinationmentioning

confidence: 99%

Section: Microb Ecol Health Dis Downloaded From Informahealthcarecommentioning

confidence: 99%