From graphite oxide to highly water dispersible functionalized graphene by single step plant extract-induced deoxygenation

Mhamane, Dattakumar; Ramadan, Wegdan; Fawzy, Manal; Rana, Abhimanyu; Dubey, Megha; Rode, Chandrashekhar V.; Lefez, B.; Hannoyer, B.; Ogale, Satishchandra

doi:10.1039/c1gc15393e

Cited by 149 publications

(93 citation statements)

References 40 publications

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“…The absorption band at around 1400 cm À1 may be due to the presence of tertiary alcohol (C-OH) group. The FTIR spectra of dried TCG shows a significant decrease in the intensities of absorption bands (O-H, C@O, C-O and tertiary C-OH bands) corresponding to the oxygen functionalities present in the graphene oxide, which establishes the deoxygenation and the results are similar to the results obtained from the graphene synthesized by using plant extracts [38].…”

Section: Ftir Studysupporting

confidence: 53%

Bioinspired reduced graphene oxide nanosheets using Terminalia chebula seeds extract

Maddinedi

Mandal

Vankayala

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

101

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Section: Ftir Studysupporting

confidence: 53%

Bioinspired reduced graphene oxide nanosheets using Terminalia chebula seeds extract

Maddinedi

Mandal

Vankayala

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

101

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“…3D porous carbons show two characteristic D and G bands located at around 1350 cm À1 and 1587 cm À1 , respectively. Usually, the former D band can be assigned to the breathing mode of j-point phonons of A 1g symmetry, while the latter G band was assigned to the E 2g phonon of sp 2 carbon atoms [30,31]. For ideal graphite, the G band should be strong and the D band should be very small [32].…”

Section: Resultsmentioning

confidence: 99%

Impregnation assisted synthesis of 3D nitrogen-doped porous carbon with high capacitance

Tang

et al. 2015

Carbon

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“…Interestingly, there were no obvious diffraction peaks of graphene observed in RES-rGO spectra, indicating that graphene sheets were homogeneously dispersed. Recently, Mhamane et al 64 have reported a facile singlestep synthesis of highly water-dispersible functionalized graphene nanosheets by plant extract-induced deoxygenation of GO. Our data indicate that GO reduction can be performed using resveratrol, which is in agreement with earlier studies using various natural products such as vitamin C, 65 l-cysteine, 66 and humanin 8 as reducing agents.…”

Section: Xrd Analysis Of Go and Res-rgomentioning

confidence: 99%

Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule

Gurunathan¹,

Han²,

Kim³

et al. 2015

IJN

158

129

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Objective Graphene represents a monolayer or a few layers of sp 2 -bonded carbon atoms with a honeycomb lattice structure. Unique physical, chemical, and biological properties of graphene have attracted great interest in various fields including electronics, energy, material industry, and medicine, where it is used for tissue engineering and scaffolding, drug delivery, and as an antibacterial and anticancer agent. However, graphene cytotoxicity for ovarian cancer cells is still not fully investigated. The objective of this study was to synthesize graphene using a natural polyphenol compound resveratrol and to investigate its toxicity for ovarian cancer cells. Methods The successful reduction of graphene oxide (GO) to graphene was confirmed by UV-vis and Fourier transform infrared spectroscopy. Dynamic light scattering and scanning electron microscopy were employed to evaluate particle size and surface morphology of GO and resveratrol-reduced GO (RES-rGO). Raman spectroscopy was used to determine the removal of oxygen-containing functional groups from GO surface and to ensure the formation of graphene. We also performed a comprehensive analysis of GO and RES-rGO cytotoxicity by examining the morphology, viability, membrane integrity, activation of caspase-3, apoptosis, and alkaline phosphatase activity of ovarian cancer cells. Results The results also show that resveratrol effectively reduced GO to graphene and the properties of RES-rGO nanosheets were comparable to those of chemically reduced graphene. Biological experiments showed that GO and RES-rGO caused a dose-dependent membrane leakage and oxidative stress in cancer cells, and reduced their viability via apoptosis confirmed by the upregulation of apoptosis executioner caspase-3. Conclusion Our data demonstrate a single, simple green approach for the synthesis of highly water-dispersible functionalized graphene nanosheets, suggesting a possibility of replacing toxic hydrazine by a natural and safe phenolic compound resveratrol, which has similar efficacy in the reduction of GO to rGO. Resveratrol-based GO reduction would facilitate large-scale production of graphene-based materials for the emerging graphene-based technologies and biomedical applications.

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From graphite oxide to highly water dispersible functionalized graphene by single step plant extract-induced deoxygenation

Cited by 149 publications

References 40 publications

Bioinspired reduced graphene oxide nanosheets using Terminalia chebula seeds extract

Bioinspired reduced graphene oxide nanosheets using Terminalia chebula seeds extract

Impregnation assisted synthesis of 3D nitrogen-doped porous carbon with high capacitance

Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule

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