COVID-19 has amplified social, economic, racial, gendered and sexual inequalities from its earliest days, yet distinct contemporary experiences of COVID-related inequalities around the globe warrant further analysis. Social scientists have theorized COVID-19 and its stratifications through various analytic axes, including critical race theory, decolonial thought and queer theory, and have identified the disparate impact of COVID-19 on LGBTQ+ communities in varied global contexts. However, the ‘queering’ of COVID-19 remains a timely project. In this article, we assess how the production and (re)production of discourses and practices that further pathologize people outside the hetero-patriarchal norm is an integral part of the ways in which a queering of COVID should be conceptualized. We understand queering COVID-19 as a theoretical stance that de-centres heteronormative and binary-gendered social structures and brings a critical eye to the normative political, biomedical and economic projects therein.