We present results of fully self-consistent Hartree-Fock based random phase approximation calculations of the strength functions S(E) and centroid energies E CEN of isoscalar (T = 0) and isovector (T = 1) giant resonances of multipolarities L = 0 -3 in 40 Ca and 48 Ca, using a wide range of commonly employed 18 Skyrme type nucleonnucleon effective interactions. We determined the sensitivities of E CEN and of the isotopic differences E CEN ( 48 Ca) -E CEN ( 40 Ca) to physical quantities, such as nuclear matter incompressibility coefficient, symmetry energy density and effective mass, associated with the Skyrme interactions and compare the results with the available experimental data.