Front Cover: Scalable and Straightforward Synthesis of All Isomeric (Cyclo)alkylpiperidines (Eur. J. Org. Chem. 23/2019)

Abstract

The Front Cover shows piperidine derivatives depicted at the magical Rubik's cube, which is falling down from the chemical space to the dark woods of possible applications. This 3D puzzle symbolizes possibility to construct all isomeric (cyclo)alkylpiperidines – advanced sp3 enriched building blocks for drug discovery. Background photo by Andriy Yakymenko; invaluable help of Vladyslava Prykhodko with artwork preparation is much appreciated. More information can be found in the Full Paper by D. M. Volochnyuk, O. O. Grygorenko et al.