Full polysaccharide chitosan-CMC membrane and silver nanocomposite: synthesis, characterization, and antibacterial behaviors

Abstract

Chitosan‐carboxymethyl cellulose (CMC) full polysaccharide membrane was prepared by cross‐linking of chitosan with CMC dialdehyde and subsequent reductive amination. CMC dialdehyde molecule was prepared by periodate oxidation of CMC and then applied as a cross‐linking agent to form a new membrane network. The properties of oxidized CMC were investigated by various methods such as Fourier transform infrared (FT‐IR) spectroscopy, 1H NMR spectroscopy, and viscosity test. Then, novel chitosan‐CMC silver nanocomposite was prepared using chitosan‐CMC as a carrier. The structure of the chitosan‐CMC membrane and the silver nanocomposite were confirmed by FT‐IR spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and thermogravimetric analysis (TGA). TEM images indicate that the chitosan‐CMC nanocomposite comprises silver nanoparticles with diameters in the range of about 5–20 nm. The antibacterial studies of the nanocomposite were also evaluated. The chitosan‐CMC silver nanocomposite demonstrates good antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Copyright © 2016 John Wiley & Sons, Ltd.

Improved antibacterial properties of an Mg‐Zn‐Ca alloy coated with chitosan nanofibers incorporating silver sulfadiazine multiwall carbon nanotubes for bone implants

“…The Ag + ‐release behavior of nanofibers could be related to two possible mechanisms: (1) diffusion from the nanofiber and (2) nanofiber degradation . The release profile shows that the nanofibers with AgSD‐MWCNTs are able to release Ag, suggesting that bacterial infection can be efficiently prevented; the antibacterial performance is sustained for a longer time period because of greater release of Ag + ions …”

“…As seen in Figure 3A 20 The release profile shows that the nanofibers with AgSD-MWCNTs are able to release Ag, suggesting that bacterial infection can be efficiently prevented; the antibacterial performance is sustained for a longer time period because of greater release of Ag + ions. [21][22][23] For evaluation of the biological response to bare alloy and nanofiber coatings, osteosarcoma MG-63 cell lines were used and cultured for 48 hours on the samples and cell adhesion and proliferation then compared. Figure 4A…”

Green synthesis of polysaccharide-based inorganic nanoparticles and biomedical aspects

“…The majority of AgNPs reported spherical shape [15,65] varied in size, between 1.1 [62] and 65.1 nm [66]. Nevertheless, shapes such as polygonal, oval-shaped, face-centered-cubic [67], irregular shape [68], rod/oval-shaped structures [69], triangular [70], and uneven shape [71] have also been documented for AgNPs.…”

In situ synthesis and properties of Ag NPs/carboxymethyl cellulose/starch composite films for antibacterial application

“…On the contrast, natural macromolecular polysaccharide with good biocompatibility and high‐molecular weight as reducing agent and stabilizer could be used to prepare environmentally friendly and stable Ag NPs . For the Ag NPs/CMC composite film, Ag NPs could be synthesized by immersing the CMC film in AgNO 3 solution via an in situ method . Besides, another strategy was that the prepared Ag NPs previously were dispersed in a matrix to form an antibacterial film .…”

“…[16][17][18][19] For the Ag NPs/CMC composite film, Ag NPs could be synthesized by immersing the CMC film in AgNO 3 solution via an in situ method. [20] Besides, another strategy was that the prepared Ag NPs previously were dispersed in a matrix to form an antibacterial film. [3] However, the former generated the waste of the remaining AgNO 3 solution, the latter formed the uneven dispersion of Ag NPs.…”