Fullerol Nanocatalysis and Trimodal Surface Plasmon Resonance for the Determination of Isocarbophos

Abstract

Fullerol (C 60 OH) has been shown to catalyze the trisodium citrate (TSC)-silver nitrate reaction to generate Ag nanoparticles (AgNPs). These AgNPs exhibit significant nanoplasmic surface-enhanced Raman scattering (SERS), resonance Rayleigh scattering (RRS), and absorption (Abs). When an aptamer (Apt) adsorbs on the C 60 OH surface, catalysis is inhibited, and the intensities of SERS, RRS, and Abs decrease. In the presence of isocarbophos (IPS), Apt forms a stable complex (Apt-IPS) and releases C 60 OH. As a result, SERS, RRS, and Abs intensities increase with increasing IPS concentration. Accordingly, a new SERS, RRS, and Abs trimodal method using Apt-labeled fullerol was established for the determination of IPS. Of the three spectral methods, SERS was the most sensitive, while the Abs method was the most cost-effective.

Alleviation of Photoreceptor Degeneration Based on Fullerenols in rd1 Mice by Reversing Mitochondrial Dysfunction via Modulation of Mitochondrial DNA Transcription and Leakage

“…[ 9 ] Water‐soluble polyhydroxylated fullerene derivatives, namely fullerenols, have a diameter of ≈1 nm with symmetrically arranged hydroxyl groups on C 60 spheres. [ 10 ] Stability for real‐time applications and intracellular localization [ 11 ] by directly crossing the cellular membrane [ 12 ] are prerequisites for fullerenols used in biomedical applications. Electron‐deficient carbon─carbon double bonds and hydroxyl groups can quench numerous electrophilic radicals; [ 13 ] this remarkable reaction to free radicals is the most important property of fullerenols.…”

Surface Activity and Aggregation Behavior of Polyhydroxylated Fullerenes in Aqueous Solutions

“…Polyhydroxylated fullerenes (PHFs)also called “fullerols” or “fullerenols”comprise a family of soluble carbon particulates that have been targeted for applications as diverse as drug delivery, metal nanoparticle catalysis, and agricultural pest control. − In part, this interest in PHFs as a functional carbon nanoparticle is driven by its ability to generate reactive oxygen species when irradiated with UV light. , PHFs have also been associated with harmful environmental and physiological outcomes, including enhanced copper release from ores and measurable phototoxicity in human epithelial cells. − Despite this intense interest in PHF properties and applications, simple questions about PHF behavior in aqueous solution remain unanswered. Specifically, accurate, quantitative descriptions of PHF surface activity and aggregation tendencies remain tentative and incomplete.…”