Functional analysis of bioprosthetic heart valves

Arcidiacono, Gabriele; Corvi, Andrea; Severi, Tamara

doi:10.1016/j.jbiomech.2004.07.007

Cited by 57 publications

(41 citation statements)

References 16 publications

(12 reference statements)

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“…For the leaflets of bioprosthetic heart valves (GA-stabilized bovine pericardium) the lowest value of the Young's modulus is 3.4AE2.7 MPa and the highest value is 91.8AE16.2 MPa. Young's moduli can additionally depend on the material's anisotropy (Arcidiacono et al, 2005). The examples listed above indicate that our results presented for the DMS-treated pericardium tissue may be potentially useful for designing new biomaterials but many additional studies with animal and human tissues should be performed.…”

Section: Discussionmentioning

confidence: 75%

“…For example, the main parameters that characterize the tissue strength are ultimate tensile strength (UTS) and toughness (Sung et al, 1999). Moreover, stress-strain curves and tissue moduli (Young's moduli) are investigated (Vincentelli et al, 1998;Sung et al, 1999;Arcidiacono et al, 2005;Martin Maestro et al, 2006). For human pericardium, the Young's modulus measured using a uniaxial load test was lower for GA-treated samples than for untreated ones (Vincentelli et al, 1998).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

An AFM study on mechanical properties of native and dimethyl suberimidate cross‐linked pericardium tissue

Matyka¹,

Matyka²,

Mróz³

et al. 2007

J of Molecular Recognition

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Changes in the stiffness of hog pericardium tissue, native and treated with dimethyl suberimidate (DMS), are investigated by atomic force microscopy (AFM). Young's modulus is calculated on the basis of the Hertz-Sneddon model. The cross-linking process increases the stiffness of the tissue. The values of Young's modulus are higher for the DMS stabilized pericardium than for the native one. We also observe that the Young's modulus of native tissue increases when the time between getting the biological material and performing the measurements is longer. This process is probably connected with natural degradation of the biological samples.

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Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 99%

An AFM study on mechanical properties of native and dimethyl suberimidate cross‐linked pericardium tissue

Matyka¹,

Matyka²,

Mróz³

et al. 2007

J of Molecular Recognition

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show abstract

“…A more rigorous and quantitative validation is challenging for our in vitro study, as we found it difficult to quantify even the basic valve performance parameters such as leaflet deformation and displacement. In fact, for most finite element studies of bioprosthetic aortic valves, due to the difficulty of quantitative experimental measurement, validation has either not been performed 2,13,22,30 or has been performed qualitatively by comparing transient leaflet deformations using images from a pulse duplicator system. 5,19 Recently, Haj-Ali et al presented a validation method that offers quantitative comparisons between experimentally measured and numerically predicted leaflet behaviors.…”

Section: Discussionmentioning

confidence: 99%

Finite Element Investigation of Stentless Pericardial Aortic Valves: Relevance of Leaflet Geometry

et al. 2010

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Recent developments in aortic valve replacement include the truly stentless pericardial bioprostheses with single point attached commissures (SPAC) implantation technique. The leaflet geometry available for the SPAC valves can either be a simple tubular or a complex three-dimensional structure molded using specially designed molds. Our main objective was to compare these two leaflet designs, the tubular vs. the molded, by dynamic finite element simulation. Time-varying physiological pressure loadings over a full cardiac cycle were simulated using ABAQUS. Dynamic leaflet behavior, leaflet coaptation parameters, and stress distribution were compared. The maximum effective valve orifice area during systole is 633.5 mm(2) in the molded valve vs. 400.6 mm(2) in the tubular valve, and the leaflet coaptation height during diastole is 4.5 mm in the former, in contrast to 1.6 mm in the latter. Computed compressive stress indicates high magnitudes at the commissures and inter-leaflet margins of the tubular valve, the highest being 3.83 MPa, more than twice greater than 1.80 MPa in the molded valve. The molded leaflet design which resembles the native valve exerts a positive influence on the mechanical performance of the SPAC pericardial valves compared with the simple tubular design. This may suggest enhanced valve efficacy and durability.

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“…The most common approach and the first step in the prediction of fatigue failure involves stress-versus-life (S-N) curves [42,54,56]. In this method, the number of cycles required to induce fatigue failure of a specimen is estimated at multiple alternating Cacciola [41] and Huang [55] utilized the theory of continuum damage mechanics, where the dynamic fatigue of the material results in progressive degradation, thereby affecting the sample's response to stress and ultimately leading to failure.…”

Section: Fatigue Modelingmentioning

confidence: 99%

Durability Assessment of Polymer Trileaflet Heart Valves

Gallocher¹

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Functional analysis of bioprosthetic heart valves

Cited by 57 publications

References 16 publications

An AFM study on mechanical properties of native and dimethyl suberimidate cross‐linked pericardium tissue

An AFM study on mechanical properties of native and dimethyl suberimidate cross‐linked pericardium tissue

Finite Element Investigation of Stentless Pericardial Aortic Valves: Relevance of Leaflet Geometry

Durability Assessment of Polymer Trileaflet Heart Valves

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