Functional Bladder Replacement
after Radical Cystectomy in the
Female: Experimental
Investigation of a New Concept

Hübner, W.; Trigo-Rocha, Flavio; Plas, Eugen; Tanagho, Emil A.

doi:10.1159/000474638

Cited by 32 publications

(12 citation statements)

References 10 publications

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“…In the course of conventional cystectomy, the autonomic nerve fibers are transected as they pass behind the ureter together with the posterior hypogastric vessels. Data ob tained by Hübner et al [8] in a study on human cadavers, and confirmed by our own experience gained in the autopsy room, clearly suggest that preservation of these nerve fibers may be technically feasible. The innervation of the somatic sphincter mechanism (the pudendal nerve) is not at risk during radical cystectomy.…”

Section: Resultssupporting

confidence: 80%

“…Hübner et al [3] verified the function of the inferior hypogastric plexus in relation to the urethral sphincter system. Pelvic nerve stimulation resulted in a pressure increase in the proximal third of the urethra, showing a typical smooth muscle reaction.…”

Section: Resultsmentioning

confidence: 98%

“…Total cystectomy sparing the urethra requires a de tailed knowledge of the anatomy of the pelvic floor, ure [3][4][5][6][7][8],…”

Section: Introductionmentioning

confidence: 99%

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Female Urethra-Sparing Cystectomy and Orthotopic Bladder Replacement

et al. 1997

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Section: Resultssupporting

confidence: 80%

Section: Resultsmentioning

confidence: 98%

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Female Urethra-Sparing Cystectomy and Orthotopic Bladder Replacement

et al. 1997

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“…Postoperatively, the ani mals were easy to handle, even the puncture of veins for laboratory control was well tolerated. Most of the reports dealing with surgical or metabolic problems of urinary diversion used dogs as the experimental animal [17][18][19], where similar conditions were described as those ob served in our experiences with pigs. In our own opinion and in the mind of German ethical committees a dog enjoys a higher standing than a domestic pig and so the experiments have to be done in pigs if they are to be equal ly meaningful.…”

Section: Discussionmentioning

confidence: 99%

Cystoplasty in Pigs: A Suitable Model for the Functional and Morphological Examination of Urinary Diversion

Jakse

1997

Urol Int

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Although in the last years surgery for urinary diversion became routine in clinical practise, various problems have to be solved. Therefore, a safe, universal animal model is necessary. An ileal pouch anastomosed to the subtotally resected urinary bladder was formed in 6 domestic pigs. Ureters remained untouched and the reservoir was not drained by any tubes. Animals were followed up for 3 months, every 3–4 weeks blood was drawn for electrolytes, renal and hepatic function and blood gas analysis. The animals were sacrificed after 3 months and a thorough pathohistological examination of the reservoir was performed. No intraoperative or operation-related postoperative complications were seen. Laboratory parameters were stable and no micturition problems appeared. Upper urinary tract was normal. The animal model presented is safe with regard to inflammatory or metabolic side effects and to disturbances of supravesical urinary tract. Therefore, this model is suitable to serve for short- as well as long-term studies of various forms of urinary diversions.

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“…Instead, the fibers coming from the pelvic plexus pass beside the lateral walls of the vagina to the bladder neck and urethra; if the lateral vaginal walls are kept intact, the majority of fibers can be saved [127]. Stenzl's anatomic studies (preceded by an experimental paper written by Hubner et al, published in 1993 [128]), have done much to promote the use of bladder substitution in women. They aimed to demonstrate the feasibility of nerve-sparing cystectomy in women: trying not only to save the pudendal nerve, but at least one band of the autonomous nerve system represented by the inferior hypogastric plexus fibers.…”

Section: Anatomic Presupposition In Womenmentioning

confidence: 99%

Bladder replacement in women: A new experience

et al. 1997

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Bladder replacement in women in a new experience. In this article the authors reviewed in a critical way the patho-physiological principles involved in the previous male bladder replacement techniques and the results achieved both leading to the recent experience of bladder replacement in women. The authors present the recent acquirements about pelvic surgical anatomy and postcystectomy oncological radicality in female, and the more common surgical techniques for building a neobladder in women with the results achieved up to now. They also examined the problems arising from this exciting but precocious experience which will surely involve the urological community in the future.

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Functional Bladder Replacement after Radical Cystectomy in the Female: Experimental Investigation of a New Concept

Cited by 32 publications

References 10 publications

Female Urethra-Sparing Cystectomy and Orthotopic Bladder Replacement

Female Urethra-Sparing Cystectomy and Orthotopic Bladder Replacement

Cystoplasty in Pigs: A Suitable Model for the Functional and Morphological Examination of Urinary Diversion

Bladder replacement in women: A new experience

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