2011
DOI: 10.1016/j.neuroimage.2011.05.088
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Functional micro-ultrasound imaging of rodent cerebral hemodynamics

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Cited by 18 publications
(20 citation statements)
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“…Male Sprague-Dawley rats (Charles River Laboratories Inc., Saint-Constant, Quebec, Canada) (N = 13) were anesthetized with isoflurane, tracheotomized, mechanically ventilated and placed on a heating pad as described in Lindvere et al (2010) and van Raaij et al (2011). The femoral artery, femoral vein and tail vein were cannulated for blood gas sampling/blood pressure monitoring, delivery of α-chloralose during imaging, and delivery of ultrasound contrast agent respectively.…”
Section: Animal Preparationmentioning
confidence: 99%
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“…Male Sprague-Dawley rats (Charles River Laboratories Inc., Saint-Constant, Quebec, Canada) (N = 13) were anesthetized with isoflurane, tracheotomized, mechanically ventilated and placed on a heating pad as described in Lindvere et al (2010) and van Raaij et al (2011). The femoral artery, femoral vein and tail vein were cannulated for blood gas sampling/blood pressure monitoring, delivery of α-chloralose during imaging, and delivery of ultrasound contrast agent respectively.…”
Section: Animal Preparationmentioning
confidence: 99%
“…Functional micro-ultrasound imaging (fMUS, (van Raaij et al, 2011)) is a recent adaptation of high-frequency ultrasound imaging (Foster et al, 2002) that allows quantitative measurement of changes in CBV and CBF. The contrast mechanism used to measure hemodynamic parameters may be either power Doppler imaging of moving red blood cells (Mace et al, 2011) or nonlinear imaging of microbubble contrast agents (van Raaij et al, 2011).…”
Section: Introductionmentioning
confidence: 99%
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“…However its use for brain functional imaging remains poorly sensitive (van Raaij et al, 2011). Various types of bubbles have been developed for imaging purpose or drug and gene delivery (Leinenga, et al, 2016).…”
Section: A C C E P T E D Accepted Manuscriptmentioning
confidence: 99%