Functional MRI, Diffusion Tensor Imaging, Magnetic Source Imaging and Intraoperative Neuromonitoring Guided Brain Tumor Resection in Awake and Under General Anaesthesia

Idris, Zamzuri; Hassan, Wan Mohd Nazaruddin Wan; Mustapha, Muzaimi; Idris, Badrisyah; Ghani, Rahman Izaini; Abdullah, Jafri Malin

doi:10.5772/52032

Cited by 6 publications

(3 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, the direct cortical brainwaves were monitored using ECoG. The gold standard of ECoG in detecting abnormal human brainwaves is well documented in epilepsy and brain mapping study (Idris et al, 2013;Benbadis et al, 2018;Vakani and Nair, 2019). With ECoG, the human brainwaves were recorded directly from the brain; thus, the obtained signals are much superior to the scalp electroencephalography (EEG).…”

Section: Direct Cortical Brainwaves Subclinical Seizures and Therapeutic Hypothermiamentioning

confidence: 93%

A Clinical Test for a Newly Developed Direct Brain Cooling System for the Injured Brain and Pattern of Cortical Brainwaves in Cooling, Noncooling, and Dead Brain

Idris

Ang

Hassan

et al. 2022

Therapeutic Hypothermia and Temperature Management

Self Cite

View full text Add to dashboard Cite

To ensure the direct delivery of therapeutic hypothermia at a selected constant temperature to the injured brain, a newly innovated direct brain cooling system was constructed. The practicality, effectiveness, and safety of this system were clinically tested in our initial series of 14 patients with severe head injuries. The patients were randomized into two groups: direct brain cooling at 32°C and the control group. All of them received intracranial pressure (ICP), focal brain oxygenation, brain temperature, and direct cortical brainwave monitoring. The direct brain cooling group did better in the Extended Glasgow Outcome Scale at the time of discharge and at 6 months after trauma. This could be owing to a trend in the monitored parameters; reduction in ICP, increment in cerebral perfusion pressure, optimal brain redox regulation, near-normal brain temperature, and lessening of epileptic-like brainwave activities are likely the reasons for better outcomes in the cooling group. Finally, this study depicts interesting cortical brainwaves during a transition time from being alive to dead. It is believed that the demonstrated cortical brainwaves follow the principles of quantum physics.

show abstract

Section: Direct Cortical Brainwaves Subclinical Seizures and Therapeutic Hypothermiamentioning

confidence: 93%

A Clinical Test for a Newly Developed Direct Brain Cooling System for the Injured Brain and Pattern of Cortical Brainwaves in Cooling, Noncooling, and Dead Brain

Idris

Ang

Hassan

et al. 2022

Therapeutic Hypothermia and Temperature Management

Self Cite

View full text Add to dashboard Cite

show abstract

“…Thus, one may say that the 'electrical wave brain network' represents a kind of mirror to 'limited projected waves' (finite physical universe items being compressed into the brain). With this view, i.e., considering the presence of limitations in both wave projection and consciousness, larger evoked electromagnetic fields are naturally observed for seeing, hearing, tasting, etc., of material objects [23,24]. At this juncture, we would like to consider the brainwaves of a dead person according to our clinical observation and our recently published manuscript [25].…”

Section: Fusion Of Electrical and Quantum Fields Inside The Brain: Fusion Of Bohmian And Quantum Mechanics And Their Algorithmsmentioning

confidence: 99%

Quantum and Electromagnetic Fields in Our Universe and Brain: A New Perspective to Comprehend Brain Function

et al. 2021

Self Cite

View full text Add to dashboard Cite

The concept of wholeness or oneness refers to not only humans, but also all of creation. Similarly, consciousness may not wholly exist inside the human brain. One consciousness could permeate the whole universe as limitless energy; thus, human consciousness can be regarded as limited or partial in character. According to the limited consciousness concept, humans perceive projected waves or wave-vortices as a waveless item. Therefore, human limited consciousness collapses the wave function or energy of particles; accordingly, we are only able to perceive them as particles. With this “limited concept”, the wave-vortex or wave movement comes into review, which also seems to have a limited concept, i.e., the limited projected wave concept. Notably, this wave-vortex seems to embrace photonic light, as well as electricity and anything in between them, which gives a sense of dimension to our brain. These elements of limited projected wave-vortex and limitless energy (consciousness) may coexist inside our brain as electric (directional pilot wave) and quantum (diffused oneness of waves) brainwaves, respectively, with both of them giving rise to one brain field. Abnormality in either the electrical or the quantum field or their fusion may lead to abnormal brain function.

show abstract

“…Neural oscillations can be further stratified into microscale-oscillation (activity of a single neuron), mesoscale-oscillation (activity of the local group of neurons or vertices) and macroscale-oscillation (neural activity from different brain regions or networks). [ 1 ] According to the graph theory, the macroscale-oscillation forms numerous network loops with edges and vertices inside our brain. [ 2 3 ] This network loops play a crucial role in both; normal and abnormal (pathological) brain function.…”

Section: Introductionmentioning

confidence: 99%

Neural oscillation, network, eloquent cortex and epileptogenic zone revealed by magnetoencephalography and awake craniotomy

et al. 2014

Self Cite

View full text Add to dashboard Cite

Background:Magnetoencephalography (MEG) is a method of functional neuroimaging. The concomitant use of MEG and electrocorticography has been found to be useful in elucidating neural oscillation and network, and to localize epileptogenic zone and functional cortex. We describe our early experience using MEG in neurosurgical patients, emphasizing on its impact on patient management as well as the enrichment of our knowledge in neurosciences.Materials and Methods:A total of 10 subjects were included; five patients had intraaxial tumors, one with an extraaxial tumor and brain compression, two with arteriovenous malformations, one with cerebral peduncle hemorrhage and one with sensorimotor cortical dysplasia. All patients underwent evoked and spontaneous MEG recordings. MEG data was processed at band-pass filtering frequency of between 0.1 and 300 Hz with a sampling rate of 1 kHz. MEG source localization was performed using either overdetermined equivalent current dipoles or underdetermined inversed solution. Neuromag collection of events software was used to study brain network and epileptogenic zone. The studied data were analyzed for neural oscillation in three patients; brain network and clinical manifestation in five patients; and for the location of epileptogenic zone and eloquent cortex in two patients.Results:We elucidated neural oscillation in three patients. One demonstrated oscillatory phenomenon on stimulation of the motor-cortex during awake surgery, and two had improvement in neural oscillatory parameters after surgery. Brain networks corresponding to clinico-anatomical relationships were depicted in five patients, and two networks were illustrated here. Finally, we demonstrated epilepsy cases in which MEG data was found to be useful in localizing the epileptogenic zones and functional cortices.Conclusion:The application of MEG while enhancing our knowledge in neurosciences also has a useful role in epilepsy and awake surgery.

show abstract

Functional MRI, Diffusion Tensor Imaging, Magnetic Source Imaging and Intraoperative Neuromonitoring Guided Brain Tumor Resection in Awake and Under General Anaesthesia

Cited by 6 publications

References 72 publications

A Clinical Test for a Newly Developed Direct Brain Cooling System for the Injured Brain and Pattern of Cortical Brainwaves in Cooling, Noncooling, and Dead Brain

A Clinical Test for a Newly Developed Direct Brain Cooling System for the Injured Brain and Pattern of Cortical Brainwaves in Cooling, Noncooling, and Dead Brain

Quantum and Electromagnetic Fields in Our Universe and Brain: A New Perspective to Comprehend Brain Function

Neural oscillation, network, eloquent cortex and epileptogenic zone revealed by magnetoencephalography and awake craniotomy

Contact Info

Product

Resources

About