Functional nanostructure-loaded three-dimensional graphene foam as a non-enzymatic electrochemical sensor for reagentless glucose detection

Liu, Qianshi; Zhong, Haining; Chen, Miao; Cheng, Zhiqing; Liu, Yan; Xi, Fengna; Luo, Tao

doi:10.1039/d0ra05553k

Cited by 55 publications

(32 citation statements)

References 51 publications

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“…The estimated pore sizes of LCNF electrodes are ca. two orders of magnitude smaller than the typical reports for graphene foam prepared by CVD [90]. This can enhance efficient interaction between the analyte and the functional interface.…”

Section: Laser-induced Carbon Nanofibersmentioning

confidence: 78%

Carbon nanomaterial hybrids via laser writing for high-performance non-enzymatic electrochemical sensors: a critical review

Simsek

Wongkaew

2021

Anal Bioanal Chem

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Non-enzymatic electrochemical sensors possess superior stability and affordability in comparison to natural enzyme-based counterparts. A large variety of nanomaterials have been introduced as enzyme mimicking with appreciable sensitivity and detection limit for various analytes of which glucose and H2O2 have been mostly investigated. The nanomaterials made from noble metal, non-noble metal, and metal composites, as well as carbon and their derivatives in various architectures, have been extensively proposed over the past years. Three-dimensional (3D) transducers especially realized from the hybrids of carbon nanomaterials either with metal-based nanocatalysts or heteroatom dopants are favorable owing to low cost, good electrical conductivity, and stability. In this critical review, we evaluate the current strategies to create such nanomaterials to serve as non-enzymatic transducers. Laser writing has emerged as a powerful tool for the next generation of devices owing to their low cost and resultant remarkable performance that are highly attractive to non-enzymatic transducers. So far, only few works have been reported, but in the coming years, more and more research on this topic is foreseeable. Graphical abstract

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Section: Laser-induced Carbon Nanofibersmentioning

confidence: 78%

Carbon nanomaterial hybrids via laser writing for high-performance non-enzymatic electrochemical sensors: a critical review

Simsek

Wongkaew

2021

Anal Bioanal Chem

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“…As a class of biomarkers, metabolites are the metabolic product of natural life activities in an organism. Reliable and sensitive detection of metabolites plays an important role in the diagnosis and prevention of diseases [ 1 , 2 , 3 , 4 , 5 ]. For instance, uric acid (UA), as the purine metabolic product, is related to many clinical diseases including renal dysfunction, chronic nephritis, renal insufficiency, gout, and cardiovascular disease, etc.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Sensor Nanoarchitectonics for Sensitive Detection of Uric Acid in Human Whole Blood Based on Screen-Printed Carbon Electrode Equipped with Vertically-Ordered Mesoporous Silica-Nanochannel Film

Yang

Liu

et al. 2022

Nanomaterials

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Screen-printed carbon electrodes (SPCEs) bear great potential in the detection of biomarker in clinical samples with low sample consumption. However, modification of electrode surfaces to improve the anti-interference ability and sensitivity is highly desirable for direct electroanalysis of whole blood samples. Here, a reliable and miniaturized electrochemical sensor is demonstrated based on SPCE equipped with vertically-ordered mesoporous silica-nanochannel film (VMSF). To achieve stable binding of VMSF and improve the electrocatalytic performance, electrochemically reduced graphene oxide (ErGO) is applied as a conductive adhesion layer, that is in situ reduced from GO nanosheets during fast growth (less than 10 s) of amino groups modified VMSF (NH2-VMSF) using electrochemically assisted self-assembly (EASA). In comparison with bare SPCE, NH2-VMSF/ErGO/SPCE exhibits decreased oxidation potential of uric acid (UA) by 147 mV owing to significant electrocatalytic ability of ErGO. The dual signal amplification based on electrocatalysis of ErGO and enrichment of nanochannels leads to enhanced peak current by 3.9 times. Thus, the developed NH2-VMSF/ErGO/SPCE sensor enables sensitive detection of UA in the range from 0.5 μM to 180 μM with a low limit of detection (LOD, 129 nM, S/N = 3). Owing to good anti-fouling ability and high selectivity of the sensor, direct and rapid detection of UA in human whole blood is realized with very low sample consumption (50 μL).

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“…Electrochemical sensors could offer a unique combination of key merits including simple instrument, convenient operation, and high sensitivity. (Liu et al, 2020;Sabbaghan et al, 2021;Xuan et al, 2021;Ghalkhani and Sohouli, 2022) The electroactive phenolic hydroxyl groups in BPA enable its detection by electrochemical sensing. To improve the detection sensitivity, researchers have used a variety of materials to modify the working electrode, including metal or metal oxide nanoparticles (Ashraf et al, 2020;Wang et al, 2020b;Yang et al, 2022), carbon materials (Yasri et al, 2015;Alam and Deen, 2020;Zhu et al, 2020;Ponnada et al, 2022;Wang et al, 2022), ionic liquids (Wang et al, 2018;Wang et al, 2021b), molecularly imprinted polymers (Beduk et al, 2020;Zhang et al, 2021), metals and covalent organic frameworks (Zhang et al, 2018;Pang et al, 2020), and aptamers (Hadi et al, 2016;Jun et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Direct and Sensitive Electrochemical Detection of Bisphenol A in Complex Environmental Samples Using a Simple and Convenient Nanochannel-Modified Electrode

Huang

Zhang

Dong³

et al. 2022

Front. Chem.

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Rapid, convenient, and sensitive detection of Bisphenol A (BPA) in complex environmental samples without the need for tedious pre-treatment is crucial for assessing potential health risks. Herein, we present an electrochemical sensing platform using a simple nanochannel-modified electrode, which enables the direct and sensitive detection of BPA in complex samples. A vertically ordered mesoporous silica-nanochannel film (VMSF) with high-density nanochannels is rapidly and stably grown on the surface of a electrochemically activated glassy carbon electrode (p-GCE) by using the electrochemically assisted self-assembly (EASA) method. The high antifouling capability of the VMSF/p-GCE sensor is proven by investigating the electrochemical behavior of BPA in the presence of model coexisting interfering molecules including amylum, protein, surfactant, and humic acid. The VMSF/p-GCE sensor can sensitively detect BPA ranged from 50 to 1.0 μM and 1.0–10.0 μM, with low detection limits (15 nM). Owing to the electrocatalytic performance and high potential resolution of p-GCE, the sensor exhibits high selectivity for BPA detection in the presence of common environmental pollutants, including bisphenol S (BPS), catechol (CC), hydroquinone (HQ), and 4-nitrophenol (4-NP). In combination with the good antifouling property of the VMSF, direct detection of BPA in environmental water samples and soil leaching solution (SLS) is also realized without separation pretreatment. The developed VMSF/p-GCE sensor demonstrated advantages of simple structure, high sensitivity, good antifouling performance, and great potential in direct electroanalysis of endocrine-disrupting compounds in complex samples.

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Functional nanostructure-loaded three-dimensional graphene foam as a non-enzymatic electrochemical sensor for reagentless glucose detection

Abstract: A non-enzymatic electrochemical sensor was fabricated by loading functional nanostructure on three-dimensional graphene foam for reagentless detection of glucose with high sensitivity and stability.

Cited by 55 publications

References 51 publications

Carbon nanomaterial hybrids via laser writing for high-performance non-enzymatic electrochemical sensors: a critical review

Carbon nanomaterial hybrids via laser writing for high-performance non-enzymatic electrochemical sensors: a critical review

Electrochemical Sensor Nanoarchitectonics for Sensitive Detection of Uric Acid in Human Whole Blood Based on Screen-Printed Carbon Electrode Equipped with Vertically-Ordered Mesoporous Silica-Nanochannel Film

Direct and Sensitive Electrochemical Detection of Bisphenol A in Complex Environmental Samples Using a Simple and Convenient Nanochannel-Modified Electrode

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