Functional outcomes of kyphoplasty for the treatment of osteoporotic and osteolytic vertebral compression fractures

Khanna, Ajai; Reinhardt, Mary-Kay; Togawa, Daisuke; Lieberman, Isador H.

doi:10.1007/s00198-006-0068-3

Cited by 59 publications

(26 citation statements)

References 38 publications

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“…However, their study did not investigate the social status of the two groups [17]. Our results regarding social function are in keeping with previous studies, which included functional outcomes following balloon kyphoplasty [23,24]. VCFs not only have patient-specific effects in terms of morbidity and mortality (Lau and co-workers quoted the mortality at 3 years at 46 % [25]), but are also a financial burden on society.…”

Section: Discussionsupporting

confidence: 85%

Social implications of balloon kyphoplasty: prospective study from a single UK centre

et al. 2012

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Purpose The incidence of osteoporotic fractures is increasing with an ageing population. This has potential consequences for health services, patients and their families. Treatment of osteoporotic vertebral compression fractures (OVCFs) has been limited to non-surgical measures so far. The social and functional consequences of balloon kyphoplasty, a recent development for the treatment of VCF, were assessed in this cohort study. Methods Data collected prospectively from 53 patients undergoing balloon kyphoplasty for symptomatic OVCF in our hospital's spinal unit were compared with data from an historical age-matched group of 51 consecutive patients treated conservatively for symptomatic OVCF. Social functionality was recorded prior to the injury, and at 6-month and 1-year follow-up; mortality was recorded at 6 months and 1 year. Results The mortality rate in the balloon kyphoplasty group was 11 % (6/53) at 1 year post-OVCF, versus 22 % (11/51) in the conservatively treated controls. A drift to a lower level of social functionality (defined by a lower level of independence) was observed at 1 year in 21 % of patients in the balloon kyphoplasty group versus 53 % of patients in the conservatively treated group. A drift to a lower level of independence was noted in 67 % of the conservatively treated patients who started at a lower level of functionality versus 20 % drift in a similar group who were treated with balloon kyphoplasty. Conclusions The reduction in mortality and drift in social functionality at 1 year following treatment with balloon kyphoplasty suggests that it is a viable option for the management of OVCFs.

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Section: Discussionsupporting

confidence: 85%

Social implications of balloon kyphoplasty: prospective study from a single UK centre

et al. 2012

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“…The overall data related to both vertebroplasty and balloon kyphoplasty are addressed in a number of publications. 5,[8][9][10][11][12][13][14][15][16][17][18][19][20] In considering the potential benefit of PMMA injection, it is necessary to be aware of the biomechanics of pathologic spine fractures (Figure 1). With the occurrence of a VCF, the center of gravity moves forward.…”

Section: Introductionmentioning

confidence: 99%

The role of vertebral augmentation in multiple myeloma: International Myeloma Working Group Consensus Statement

et al. 2008

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“…Eine frühzei-tig durchgeführte Kyphoplastie erlaubt bei frischen Wirbelfrakturen naturgemäß eine bessere Wiederaufrichtung der eingebrochenen Wirbelkörper, da es noch nicht zur vollständigen kallösen Verheilung an den Frakturlinien gekommen ist. [17,36,40,46]. Allerdings erfahren viele Patienten mit frischen oder älteren Wirbelkörperfrakturen auch ohne einen operativen Eingriff innerhalb weniger Tage oder Wochen einen deutlichen Beschwerderückgang oder werden sogar vollstän-dig schmerzfrei, wobei dieser erfreuliche Beschwerdeverlauf einem normalen Frakturheilungsverlauf entspricht.…”

Section: Wahl Des Zeitpunktsunclassified

Indications and results of kypho- and vertebroplasty

et al. 2008

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The best currently available evidence based treatment reduces vertebral fracture risk but does not totally prevent osteoporotic and malignant follow-up fractures. Kyphoplasty and vertebroplasty are options of a causal treatment to reduce pain by internal stabilization of fractured vertebrae. The indication for these minimal invasive procedures requires an interdisciplinary discussion of the individual case to guarantee technical feasibility, to increase the likelihood that these procedures will indeed reduce pain and to embed these procedures into the long term therapeutic concept of every single patient. In addition to internal stabilization of a painfully fractured vertebra kyphoplasty also seeks to restore lost vertebral height which appears promising in acute vertebral fractures. Due to the procedure there are more cement leakages after vertebroplasty. Available controlled prospective studies demonstrate only for kyphoplasty a long-term benefit for the patient in terms of pain reduction, increased mobility and improved quality of life.

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Functional outcomes of kyphoplasty for the treatment of osteoporotic and osteolytic vertebral compression fractures

Cited by 59 publications

References 38 publications

Social implications of balloon kyphoplasty: prospective study from a single UK centre

Social implications of balloon kyphoplasty: prospective study from a single UK centre

The role of vertebral augmentation in multiple myeloma: International Myeloma Working Group Consensus Statement

Indications and results of kypho- and vertebroplasty

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