Functional Silanes as Surface Modifying Primers for the Preparation of Highly Stable and Well-Defined Magnetic Polymer Hybrids

Abstract

A general and versatile method for the functionalization and subsequent modification of single dispersed magnetite nanoparticles by direct reaction of alkoxysilanes on the particle surface is reported. Our data supports the formation of a dense monolayer that is controlled by sterical needs. By selecting the functionality of alkoxysilanes, the surface properties of the particles can be tailored. Depending on the surface functionality, the modified particles can be used as macrocomonomers or macrocrosslinkers, or as macroinitiators for surface-initiated polymerization and thus enable the covalent attachment of polymers.

3-Aminopropylsilane-modified iron oxide nanoparticles for contrast-enhanced magnetic resonance imaging of liver lesions induced by <em>Opisthorchis felineus</em>

“…[17][18][19] One of the most effective methods of modification is the covalent modification of MNP surface using various alkoxysilane reagents. 20 Alkoxysilanes are commercially available reagents that contain various functional groups such as amino, [21][22][23][24][25][26][27][28] mercapto, [26][27][28][29] glycidyloxy, 26,30,31 cyano, 27,32 carboxylic, aldehyde, and isocyanate 27 groups. Following the modification, alkoxysilanes form a cross-linked silicone layer with functional groups covering the surface of nanoparticles.…”

Preparation of core–shell magnetic ion-imprinted polymer for selective extraction of Pb(II) from environmental samples

“…Over the past few decades, Fe 3 O 4 particles, one of magnetic particles, have attracted worldwide attention because of their unique physical and chemical properties, biocompatibility and remarkable magnetic properties [6][7][8][9]. However, the traditional coating of Fe 3 O 4 particles cannot separate analytes efficiently from the complex biological or environmental samples.…”

Quantitative Determination of 3-Aminopropylsilane on the Surface of FE3O4 Nanoparticles by Attenuated Total Reflection Infrared Spectroscopy

“…Magnetic materials are used routinely, e.g., in biology for magnetic separation of biomolecules and cells [4] or in chemistry for development of magnetic separation of catalysts [5]. A promising method for modifying iron-oxide nanoparticles (NP) consists of depositing an organic layer on MNP using functionalized alkoxysilanes, in particular, 3-aminopropyltrialkoxysilanes [6][7][8][9][10][11][12][13][14][15][16][17][18] that form an organosilicon layer with functional groups on the surface. This enables the NP to be modifi ed further.…”

“…IR spectroscopy is most often employed for a qualitative assessment of the degree of functionalization. As a rule, elemental analysis, inductively coupled plasma atomic-emission spectroscopy (AES), or thermogravimetric analysis (TGA) is used for a quantitative determination of the number of organic molecules on the MNP surface [6][7][8][10][11][12][13][14].…”