Functionalization of silver nanoparticles with mPEGylated luteolin for selective visual detection of Hg<sup>2+</sup> in water sample

Qing, Weixia; Zhao, Mengnan; Kou, Conghui; Lu, Minghua; Wang, Yong

doi:10.1039/c8ra05243c

Cited by 30 publications

(6 citation statements)

References 25 publications

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“…As depicted in Figure 5a, the absorbance intensity at 520 nm exhibited slight changes with an increase in NaCl concentration from 1 to 7 mM, resulting in a negligible color change due to alterations in surface charge. 93 However, the sensitivity of CHP@AgNPs toward streptomycin significantly increased with optimized ionic strength (Figure 5a), indicating that the appropriate adjustment of the ionic strength can enhance the absorbance signal and overall performance of the developed biosensor. This suggests that Na + cations enhance the sensitivity of the analytical system by readily interacting with the negatively charged CHP@AgNPs, leading to a net positive surface charge.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Development of Novel Peptide-Modified Silver Nanoparticle-Based Rapid Biosensors for Detecting Aminoglycoside Antibiotics

Kim,

Sharma,

Rasool

et al. 2023

J. Agric. Food Chem.

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The detection and monitoring of aminoglycoside antibiotics (AGAs) have become of utmost importance due to their widespread use in human and animal therapy, as well as the associated risks of exposure, toxicity, and the emergence of antimicrobial resistance. In this study, we successfully synthesized casein hydrolysate peptides-functionalized silver nanoparticles (CHPs@AgNPs) and employed them as a novel colorimetric analytical platform to demonstrate remarkable specificity and sensitivity toward AGAs. The colorimetric and spectral response of the CHPs@AgNPs was observed at 405 and 520 nm, showing a linear correlation with the concentration of streptomycin, a representative AGA. The color changes from yellow to orange provided a visual indication of the analyte concentration, enabling quantitative determination for real-world samples. The AgNP assay exhibited excellent sensitivity with dynamic ranges of approximately 200−650 and 100−700 nM for streptomycin-spiked tap water and dairy whey with limits of detection found to be ∼98 and 56 nM, respectively. The mechanism behind the selective aggregation of CHPs@AgNPs in the presence of AGAs involves the amine groups of the target analytes acting as molecular bridges for electrostatic coupling with hydroxyl or carboxyl functionalities of adjacent NPs, driving the formation of stable NP aggregates. The developed assay offers several advantages, making it suitable for various practical applications. It is characterized by its simplicity, rapidity, specificity, sensitivity, and cost-effectiveness. These unique features make the method a promising tool for monitoring water quality, ensuring food safety, and dealing with emergent issues of antibiotic resistance.

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Section: ■ Results and Discussionmentioning

confidence: 99%

Development of Novel Peptide-Modified Silver Nanoparticle-Based Rapid Biosensors for Detecting Aminoglycoside Antibiotics

Kim,

Sharma,

Rasool

et al. 2023

J. Agric. Food Chem.

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“…Excessive inflammation can be damaging, and especially to the appearance of the skin. Cyclooxygenases (COX-1 and COX-2) are critical players in inflammation that have been demonstrated to be suppressed by several medicinal plant extracts, which has demonstrated the anti-inflammatory capabilities of these extracts [52,53]. The tradi-tional use of S. virginianum as an anti-inflammatory agent has been proposed in previous reports [54].…”

Section: Anti-inflammatory Evaluationmentioning

confidence: 99%

Comparative Analysis of Various Plant-Growth-Regulator Treatments on Biomass Accumulation, Bioactive Phytochemical Production, and Biological Activity of Solanum virginianum L. Callus Culture Extracts

et al. 2022

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Solanum virginianum L. (Solanum xanthocarpum) is an important therapeutic plant due to the presence of medicinally useful plant-derived compounds. S. virginianum has been shown to have anticancer, antioxidant, antibacterial, antiaging, and anti-inflammatory properties. This plant is becoming endangered due to overexploitation and the loss of its native habitat. The purpose of this research is to develop an ideal technique for the maximum biomass and phytochemical accumulation in S. virginianum leaf-induced in vitro cultures, as well as to evaluate their potential antiaging, anti-inflammatory, and antioxidant abilities. Leaf explants were grown on media (Murashige and Skoog (MS)) that were supplemented with various concentrations and combinations of plant hormones (TDZ, BAP, NAA, and TDZ + NAA) for this purpose. When compared with the other hormones, TDZ demonstrated the best response for callus induction, biomass accumulation, phytochemical synthesis, and biological activities. However, with 5 mg/L of TDZ, the optimal biomass production (FW: 251.48 g/L and DW: 13.59 g/L) was estimated. The highest total phenolic level (10.22 ± 0.44 mg/g DW) was found in 5 mg/L of TDZ, whereas the highest flavonoid contents (1.65 ± 0.11 mg/g DW) were found in 10 mg/L of TDZ. The results of the HPLC revealed that the highest production of coumarins (scopoletin: 4.34 ± 0.20 mg/g DW and esculetin: 0.87 ± 0.040 mg/g DW) was determined for 10 mg/L of TDZ, whereas the highest accumulations of caffeic acid (0.56 ± 0.021 mg/g DW) and methyl caffeate (18.62 ± 0.60 mg/g DW) were shown by 5 mg/L of TDZ. The determination of these phytochemicals (phenolics and coumarins) estimates that the results of our study on biological assays, such as antioxidant, anti-inflammatory, and antiaging assays, are useful for future cosmetic applications.

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“…It has been suggested that luteolin can be applied for removal and also the determination of Pb(II) . The color-changing of the mPEGylated functionalized luteolin-AgNPs (Figure - 10b ) from yellow–brown to colorless was utilized as an aggregation-based sensing system for highly sensitive and selective detection of Hg(II) in tap water samples in the presence of other metal cations …”

Section: Optical (Bio)sensing Applications Of Phytochemicalsmentioning

confidence: 99%

“…75 The colorchanging of the mPEGylated functionalized luteolin-AgNPs (Figure 12-10b) from yellow−brown to colorless was utilized as an aggregation-based sensing system for highly sensitive and selective detection of Hg(II) in tap water samples in the presence of other metal cations. 76 Biochanin A is a natural O-methylated isoflavone with a characteristic fluorescence emission at 471 nm that is generally extracted from Eupatorium adenophorum leaves. Owing to its fluorescence quenching property in the presence of Cu(II) via an intramolecular charge transfer, Biochanin A (Figure 12-11a) has been used as an optical probe for sensitive determination of Cu(II) down to 1 μM.…”

mentioning

confidence: 99%

Phytochemicals toward Green (Bio)sensing

et al. 2020

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Because of numerous inherent and unique characteristics of phytochemicals as bioactive compounds derived from plants, they have been widely used as one of the most interesting nature-based compounds in a myriad of fields. Moreover, a wide variety of phytochemicals offer a plethora of fascinating optical and electrochemical features that pave the way toward their development as optical and electrochemical (bio)sensors for clinical/ health diagnostics, environmental monitoring, food quality control, and bioimaging. In the current review, we highlight how phytochemicals have been tailored and used for a wide variety of optical and electrochemical (bio)sensing and bioimaging applications, after classifying and introducing them according to their chemical structures. Finally, the current challenges and future directions/perspective on the optical and electrochemical (bio)sensing applications of phytochemicals are discussed with the goal of further expanding their potential applications in (bio)sensing technology. Regarding the advantageous features of phytochemicals as highly promising and potential biomaterials, we envisage that many of the existing chemical-based (bio)sensors will be replaced by phytochemical-based ones in the near future.

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Functionalization of silver nanoparticles with mPEGylated luteolin for selective visual detection of Hg²⁺ in water sample

Abstract: A novel colorimetric sensor for selective detection of Hg2+ based on mPEGylated luteolin functionalized silver nanoparticles was prepared.

Cited by 30 publications

References 25 publications

Development of Novel Peptide-Modified Silver Nanoparticle-Based Rapid Biosensors for Detecting Aminoglycoside Antibiotics

Development of Novel Peptide-Modified Silver Nanoparticle-Based Rapid Biosensors for Detecting Aminoglycoside Antibiotics

Comparative Analysis of Various Plant-Growth-Regulator Treatments on Biomass Accumulation, Bioactive Phytochemical Production, and Biological Activity of Solanum virginianum L. Callus Culture Extracts

Phytochemicals toward Green (Bio)sensing

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Functionalization of silver nanoparticles with mPEGylated luteolin for selective visual detection of Hg2+ in water sample

Abstract: A novel colorimetric sensor for selective detection of Hg2+ based on mPEGylated luteolin functionalized silver nanoparticles was prepared.

Cited by 30 publications

References 25 publications

Development of Novel Peptide-Modified Silver Nanoparticle-Based Rapid Biosensors for Detecting Aminoglycoside Antibiotics

Development of Novel Peptide-Modified Silver Nanoparticle-Based Rapid Biosensors for Detecting Aminoglycoside Antibiotics

Comparative Analysis of Various Plant-Growth-Regulator Treatments on Biomass Accumulation, Bioactive Phytochemical Production, and Biological Activity of Solanum virginianum L. Callus Culture Extracts

Phytochemicals toward Green (Bio)sensing

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Functionalization of silver nanoparticles with mPEGylated luteolin for selective visual detection of Hg²⁺ in water sample