Functionalized Gold Nanoparticles: Synthesis, Properties and Biomedical Applications

Abstract

Gold nanoparticles have excellent optical and plasmon properties and have enormous research potential when they combine with different ligands. Functionalized gold nanoparticles are widely used in drug delivery, biological detection, sensors, and even clinical treatment. At present, with the rapid development of functionalized gold nanoparticles, we think it is necessary to sort out the recent research results. In this paper, the synthesis, characteristics, and biological applications of the three aspects are introduced. Firstly, the synthetic methods of functionalized gold nanoparticles are reviewed, and the improvement of the commonly used synthetic methods is summarized. Then, the catalytic properties, oxidation resistance, and chirality optical properties are summarized in detail. Finally, we summarize the research progress in the field of biology in recent years.

Plasmonic Gold Nanoparticles (AuNPs): Properties, Synthesis and their Advanced Energy, Environmental and Biomedical Applications

“…Few to mention here are; general reviews where researchers have tried to provide a summarized overview on the AuNPs synthesis, properties, and applications. [24][25][26] Some reviews have discussed the synthesis of AuNPs via different routes. [27,28] A review on the synthesis of functionalized AuNPs, where the authors report various functionalization strategies to control the surface properties.…”

“…Due to extensive research and the importance of AuNPs in various sectors, various review articles have been published over the years. Few to mention here are; general reviews where researchers have tried to provide a summarized overview on the AuNPs synthesis, properties, and applications [24–26] . Some reviews have discussed the synthesis of AuNPs via different routes [27,28] .…”

Benchmarking the ACEnano Toolbox for Characterisation of Nanoparticle Size and Concentration by Interlaboratory Comparisons

“…An increasing number of nanomaterials (NMs) are entering the market in consumer products spanning from health care and leisure to electronics, cosmetics and foodstuff. Nanotechnology is a truly enabling technology, with unlimited potential for innovation and numerous benefits derived from the NM unique size-related properties that are widely recognised [ 1 , 2 ]. However, the novel and dynamic properties and range of forms of NMs make the development of a well-founded and robust legislative framework to ensure the safe development of nano-enabled products particularly challenging.…”

Gold Nanoparticles Synthesis and Antimicrobial Effect on Fibrous Materials

“…However, usage of citric acid, sodium borohydride (NaBH 4 ), polyethylene glycol (PEG), hexadecyltrimethylammonium bromide (CTAB), trioctyl-phosphine (TOPO), and oleyl amine (OAm) showed to be toxic, harmful, irritating, flammable, or hazardous to the environment. Therefore, green synthesis methods were introduced recently, where chemical reducing agents are being replaced by plant extracts, bacteria, yeasts, fungi, and enzymes [ 13 , 14 ].…”