Functionalized Graphene Tagged Polyurethanes for Corrosion Inhibitor and Sustained Drug Delivery

Abstract

Surface functionalization of graphene oxide with sulfonate group and subsequent grafting with polyurethane chains leads to the significant improvement in the properties of polymer and modified graphene as a filler. Modification of graphene oxide is revealed through spectroscopy while grafting of polymer chain over sulfonated graphene is confirmed through 1H NMR and other techniques. Higher order of self-assembly phenomena is observed in nanohybrids as compared to pure polymer through greater interaction between polymer chain and sulfonated graphene. Significant improvement in corrosion inhibition phenomena is observed using nanohybrids at low concentration as compared to pure polymer indicating its superior efficiency as a corrosion inhibitor. Nanohybrids also exhibit better biocompatible nature in lower concentration of filler with considerable sustained release of drug vis-à-vis pure polymer suggest its potential to use as a biomaterial for tissue engineering applications.

Supramolecular self-assembly, DNA interaction, antibacterial and cell viability studies of Cu(II) and Ni(II) complexes derived from NNN donor Schiff base ligand

“…It is also clear that among the complexes 1 and 2, complex 1 shows higher cell viability. The biocompatible nature is also evident from cell morphology obtained through fluorescence images of Hela cells of metal complexes after staining with acridine orange and ethidium bromide dye[66] (Fig. 9 & 11).…”

Fluorescent‐functionalized graphene oxide for selective labeling of tumor cells

“…The brownish solid product was obtained after filtration, and the product had been washed thoroughly with distilled water and dried at 65 °C. Sulfonate‐functionalized graphene oxide (GS) was synthesized using ammonium sulfate as described earlier . At first, ammonium sulfate and graphene oxide were added in distilled water in a ratio of 1:5 (w/w) followed by the ultrasonication for 40 min.…”

“…The brownish solid product was obtained after filtration, and the product had been washed thoroughly with distilled water and dried at 65 C. Sulfonate-functionalized graphene oxide (GS) was synthesized using ammonium sulfate as described earlier. 19 At first, ammonium sulfate and graphene oxide were added in distilled water in a ratio of 1:5 (w/w) followed by the ultrasonication for 40 min. The reaction mixture was then allowed to dry completely and heated at 245 C for 1 h. After decomposition of (NH 4 ) 2 SO 4 at 245 C, produces SO 3 species which react with the carbon through its surface hydrogen atom to form the −SO 3 H functionality in a graphene sheet.…”

Grafted cyclodextrin as carrier for control drug delivery and efficient cell killing

“…Polyurethanes (PU) are synthetic polymers having characteristic urethane group. They are mostly prepared by the reaction between diisocyanate, diols, and polyols . The wider range of starting materials leads to synthesis of polymers with different and unique properties.…”

“…They are mostly prepared by the reaction between diisocyanate, diols, and polyols. 18 The wider range of starting materials leads to synthesis of polymers with different and unique properties. The structural diversity of polyurethane allows both inter-and intramolecular interaction between different macromolecules.…”