Functionally graded hydroxyapatite-alumina-zirconia biocomposite: Synergy of toughness and biocompatibility

Afzal, Mohammad Atif Faiz; Kesarwani, Pallavi; Reddy, Kolan Madhav; Kalmodia, Sushma; Basu, Bikramjit; Balani, Kantesh

doi:10.1016/j.msec.2012.03.003

Cited by 116 publications

(81 citation statements)

References 46 publications

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“…1b, due to the different layers with the different HA contents. And the strong interfacial binding nature of the functionally graded PEEK-HA composite materials has great advantages over other functionally graded biomaterials for implant applications [15,16]. From the EDX analysis of Fig.…”

Section: Methodsmentioning

confidence: 99%

Mechanical performance and in vivo bioactivity of functionally graded PEEK–HA biocomposite materials

Lin

Luo

et al. 2014

J Sol-Gel Sci Technol

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A functionally graded material (FGM) of polyetheretherketone (PEEK)-hydroxyapatite (HA) with a symmetrical three-layer structure containing 8.7, 2.6 and 8.7 vol% HA, respectively, is successfully fabricated by hot pressing and evaluated by scanning electron microscopy and tensile testing. A good bonding between the HA particles and the PEEK matrix is achieved by virtue of an in situ method in fabricating each PEEK-HA composite layer. There are no apparent microcracks and microscopic interfaces within each layer of the FGM. The symmetrical PEEK-HA FGM does not fall apart or delaminate during loading with a tensile strength of 86.2 MPa, and its fracture energy is 56.5 kJ/m 2 . Furthermore, in vivo bioactivity of the FGM sample is also evaluated, showing that it has sound biocompability and bioactivity. Accordingly, the FGM in the future may be a promising biomaterial to be used as replacement implant of human bone through a proper design to balance mechanical properties and bioactivity.

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Section: Methodsmentioning

confidence: 99%

Mechanical performance and in vivo bioactivity of functionally graded PEEK–HA biocomposite materials

Lin

Luo

et al. 2014

J Sol-Gel Sci Technol

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“…Improved performance of the thermal and mechanical properties of FGMs has led to many different applications of them. These applications include, but not limited to, thermal barrier coatings (Baig et al 2014), biomaterials (Afzal et al 2012), wear resistant cutting tools (Garcia & Pitonak 2013), and micro-electro-mechanical-systems (MEMS) (Eshraghi et al 2015). Cylindrical structures made of FGMs have applications in the aerospace and the automotive industries, as well (Han et al 2001).…”

Section: Transient Stress Intensity Factors Of Functionally Graded Homentioning

confidence: 99%

Transient Stress Intensity Factors of Functionally Graded Hollow Cylinders with Internal Circumferential Cracks

Eshraghi

Soltani

Rajabi

2016

Lat. Am. j. solids struct.

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“…Hydroxyapatite-Alumina-Zirconia (HApAl 2 O 3 YSZ) FGM is another form of Alumina-Zirconia biocomposite which does not only hold superior physical properties but also have higher influence on cell adhesion. 44) …”

Section: Alumina-zirconia Composite Ceramicmentioning

confidence: 99%

In vivo and in vitro outcomes of alumina, zirconia and their composited ceramic-on-ceramic hip joints

Rahman

Choudhury

Osman

et al. 2013

J. Ceram. Soc. Japan

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Despite of brittleness, Ceramic-on-Ceramic (CoC) hip joints are appealing to arthritic patients because of its low friction rate, high wear resistance and low risk of osteolysis. The objectives of the study were to review and summarize the performance of Alumina, Zirconia and their functional graded material (FGM) for artificial hip joints in vivo and vitro outcomes. The Method of the study was scoping review which focused on the peer reviewed journals containing with alumina, zirconia and alumina zirconia FGM to CoC hip prosthesis. Advanced version of Alumina CoC was found to have excellent hardness but low fracture toughness. Alumina CoC hip joints was found to have a revision rate as high as 5% after 20 clinical outcomes. Zirconia ceramic had high fracture toughness but relatively low hardness when compared to Alumina ceramic. Alumina-Zirconia FGM consists both high hardness (outer surface) and improved fracture toughness (inner core) which led to better mechanical and tribological properties. However, to date, there is still no literature was found to have long period of clinical outcomes. No article was screened carrying out durability study of Alumina/Zirconia FGM for CoC hip joints with appropriate tribological experiment. Alumina/ Zirconia FGM could be very effective for long term durability of CoC hip joints. Nevertheless, this FGM needs to be investigated under appropriate tribological tests considering dynamic loadings, dimension and shape of the joints, lubricant similar to synovial fluid and large number of cycles. The long term clinical outcomes also need to be published to increase its acceptability to young active patients.

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Functionally graded hydroxyapatite-alumina-zirconia biocomposite: Synergy of toughness and biocompatibility

Cited by 116 publications

References 46 publications

Mechanical performance and in vivo bioactivity of functionally graded PEEK–HA biocomposite materials

Mechanical performance and in vivo bioactivity of functionally graded PEEK–HA biocomposite materials

Transient Stress Intensity Factors of Functionally Graded Hollow Cylinders with Internal Circumferential Cracks

In vivo and in vitro outcomes of alumina, zirconia and their composited ceramic-on-ceramic hip joints

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