Functionally substituted aromatic aldehydes as reagents in the synthesis of new substituted thioglycolurils

Abstract

Simple approach to the synthesis of 2-(4(2)- (((4,6-dialkyl-5-oxo-2-thioxohexahydroimidazo[4,5-d]imidazol-1(2H)-yl)imino)methyl)phenoxy)acetates or acetamides (new substituted thioglycolurils) based on the reaction of 5,7-dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazine-6-ones with functionally substituted aromatic aldehydes has been developed. Synthesized thioglycolurils with acetate function can undergo further simple transformation to the corresponding acetamides.