We consider k-dimensional random simplicial complexes that are generated from the binomial random (k + 1)-uniform hypergraph by taking the downward-closure, where k ≥ 2. For each 1 ≤ j ≤ k − 1, we determine when all cohomology groups with coefficients in F 2 from dimension one up to j vanish and the zero-th cohomology group is isomorphic to F 2 . This property is not deterministically monotone for this model of random complexes, but nevertheless we show that it has a single sharp threshold. Moreover we prove a hitting time result, relating the vanishing of these cohomology groups to the disappearance of the last minimal obstruction. We also study the asymptotic distribution of the dimension of the j-th cohomology group inside the critical window. As a corollary, we deduce a hitting time result for a different model of random simplicial complexes introduced in [Linial and Meshulam, Combinatorica, 2006], a result which was previously only known for dimension two [Kahle and Pittel, Random Structures Algorithms, 2016].