Grinding machines that employ a high-speed reciprocating worktable or wheel head are known as high-speed reciprocation grinding. Grinding heat generated in the high-speed reciprocation grinding process is low. Therefore, it is considered that the high-speed reciprocation grinding is suitable for grinding material of low thermal conductivity. In this study, the high-speed reciprocation grinding is applied to grind nickel-based super alloy “Waspaloy” which is known as difficult-to-cut material. And grinding characteristics of Waspaloy are investigated. As a result, it is found that the effect of grinding heat is smaller than the effect of grain depth of cut in grinding process of Waspaloy.