Fundamental limits of positron emission mammography

Moses, W.W.; Qi, Jinyi

doi:10.1016/s0168-9002(02)01895-8

Cited by 26 publications

(14 citation statements)

References 19 publications

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“…In comparison the CYBPET with two parallel planes, the CYBPET has more sensitivity because of its whole 3601 coverage that will reduce the scan time (or increase patient frequency) and or the injected dose which can compensate the increased price of CYBPET in a duration of time. Furthermore, it has been shown that [28] the images from the parallel plane PEM will suffer from some blurring or degraded spatial resolution, because of the large gap in the angular coverage.…”

Section: Resultsmentioning

confidence: 99%

CYBPET: a cylindrical PET system for breast imaging

Karimian

Thompson

Sarkar

et al. 2005

Nuclear Instruments and Methods in Physics Research Section A:

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We propose a Cylindrical Breast PET (CYBPET) system for breast imaging with patients in the prone position. An individual pendulous breast is covered by thin plastic to provide reduced pressure fixation and surrounded by the crystals inside the CYBPET ring. Each breast is imaged separately. The rest of the body is shielded properly to minimize the contribution of scattered photons from the other breast and the rest of the body. To compare the CYBPET with whole-body PET (WB-PET) the simulations of CYBPET and a WB-PET (GE-Advance) for a 10 mm tumor inside the breast with a lesion to background (breast) activity concentration of 6 to 1 were made. The noise effective count rate (NECR) of CYBPET is about twice that of WB-PET at activity concentrations less than 3.1 mCi/cc. The spatial resolution of CYBPET is better by 25% than the WB-PET. r

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Section: Resultsmentioning

confidence: 99%

CYBPET: a cylindrical PET system for breast imaging

Karimian

Thompson

Sarkar

et al. 2005

Nuclear Instruments and Methods in Physics Research Section A:

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“…Focal Plane Tomography (FPT) is one of the algorithms that can be used in PEM for image reconstruction [8]. This method consists in finding the positions of intersection between the lines of response (LOR's) within the field of view (FOV) of the scanner and what it is called a "focal plane".…”

Section: Depth-of-interaction and Image Reconstructionmentioning

confidence: 99%

Numerical evaluation of a positron emission mammography scanner using GATE

Torres-Urzúa

Alva‐Sánchez

Martínez‐Dávalos

et al. 2016

AIP Conference Proceedings

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Absorbed dose distribution in liquid water for a CyberKnife VSI using radiochromic EBT3 film AIP Conference Proceedings 1747, 060004 (2016) Abstract. In this work, a Monte Carlo simulation of a positron emission mammography (PEM) prototype under development at the Institute of Physics, UNAM, is presented. The simulated geometry included two parallel detector modules with a 73 mm separation. Each module consisted of 3 detector blocks, each one formed by an array of 38×38 lutetium yttrium orthosilicate crystal elements of 1.96×1.96×10 mm 3 at 2 mm pitch. An energy resolution of 26% for 511 keV photons, a 350-650 keV energy window and a 6 ns coincidence window were assumed. Image reconstruction was performed using focal plane tomography. Spatial resolution was assessed through the point spread function at different positions within the field of view (FOV). In addition, image quality was evaluated following the NEMA NU 4-2008 protocol. Different depth-of-interaction (DOI) assumptions were considered. The best spatial resolution (0.75 mm FWHM) was obtained when depth-of-interaction information was used, deteriorating drastically to 2.21 mm when DOI is unknown. The overall sensitivity of the system was 2.50%.

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“…Positron emission mammography (PEM) systems consist of two parallel detectors that do not rotate, and these provide slice data parallel to detectors using focal plane tomographic techniques (or limited-angle tomography) (Fig. 24) [86,87]. Usually, the breasts are compressed by the detector head to spread out breast tissues and provide a view similar to that of X-ray mammography [88].…”

Section: Breast-dedicated Positron Imaging Systemsmentioning

confidence: 99%

“…The shortcomings of these PEM systems using focal plane tomography that received most attention are the significant image blurring that occurs along the axis perpendicular to the detector plane and the broad background noise, which reduces image contrast [21,89]. Although an iterative reconstruction algorithm that provides accurate modeling of statistical noise and detector response was devised to solve the above problems due to limited angular coverage of PEM systems with two parallel detectors, convergence required several hours depending on data size [87]. Widening the angular coverage by rotating the planar detectors or utilizing a full ring or rectangular camera geometry provide the most direct ways of coping with the limitations of limited-angle tomography and of providing isotropic resolution in all three dimensions.…”

Section: Breast-dedicated Positron Imaging Systemsmentioning

confidence: 99%

Technical Advances in Current PET and Hybrid Imaging Systems

Lee¹

2010

TONMEDJ

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Abstract:The continuing efforts of investigators to achieve the best physical and clinical performances from PET (positron emission tomography) and related hybrid cameras (PET/CT and PET/MRI) have led to remarkable technical advances in hardware and software.Time of flight (TOF) information measurement, which has been enabled thanks to the invention of fast, heavy crystals and advances in fast light detection sensors and readout electronics, is used to obtain the PET images of better quality and lesion-detection performance. Statistical reconstruction with resolution recovery and measurements of depth of interaction (DOI) are the useful software-and hardware-wise approaches for enhancing the spatial resolution of reconstructed PET images. These technical advances along with an expansive increase in the number of PET and PET/CT examinations performed are facilitating the widespread use of PET scanners with specific detector structures and arrangements for particular applications or organs. Combined multimodal imaging systems are also in the development mainstream of these PET systems.In this paper, these important technologies (TOF measurements, statistical reconstruction with resolution recovery, DOI detectors, and application-specific PET cameras) that have made major contributions to advances in state-of-the-art clinical and preclinical PET and hybrid systems are reviewed.

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Fundamental limits of positron emission mammography

Cited by 26 publications

References 19 publications

CYBPET: a cylindrical PET system for breast imaging

CYBPET: a cylindrical PET system for breast imaging

Numerical evaluation of a positron emission mammography scanner using GATE

Technical Advances in Current PET and Hybrid Imaging Systems

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