Fundus Autofluorescence in Choroidal Metastatic Lesions

Abstract

Amelanotic choroidal metastases with hyperpigmentation are associated with increased FAF in most cases. Subretinal fluid overlying choroidal metastases may cause FAF as well.

Autofluorescence of intraocular tumours

“…Collet et al [10] reviewed eight eyes with choroidal metastases and correlated autofluorescence with the clinical features using a confocal scanning laser ophthalmoscope and demonstrated correlation between the presence of hyperpigmentation (lipofuscin pigment) and hyperautofluorescence (Fig. 3).…”

“…In general, hyperautofluorescence is a sign of recent onset disease (within few months), whereas hypoautofluorescence represents more chronic disease (several months or years). Patterns of hyperautofluorescence and hypoautofluorescence have been [9][10][11][12] (Tables 1 and 2). In this article, we specifically examine the features of autofluorescence related to intraocular tumours.…”

Autofluorescence of treated retinoblastoma

“…The autofluorescent features of choroidal tumors such as melanoma, nevus, and metastasis have been described in the literature. [3][4][5][6][7] In this analysis, we evaluate the AF of treated retinoblastomas and correlate these findings with clinical features.…”

Diagnostic Techniques: Autofluorescence

“…Collet et al reported 15 metastatic tumors in 14 eyes of 11 consecutive patients concluding that amelanotic choroidal metastases with hyperpigmented foci are associated with increased SW-AF in most of the cases and that subretinal fl uid overlying choroidal metastasis may cause increases in SW-AF as well [ 18 ]. Ishida et al reported two cases of metastatic choroidal tumors, concluding that the AF pattern of these cases was approximately the reverse picture of fl uorescein angiography pattern [ 19 ].…”