Fungal fragments and undocumented conidia function as new aeroallergen sources

Green, Brett James; Sercombe, J.K.; Tovey, Euan R.

doi:10.1016/j.jaci.2005.02.009

Cited by 132 publications

(91 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fungi are abundant in the environment and they have a great ability to grow either as saprophytes colonizing nonliving organic substrate or as pathogens penetrating living tissues, from where they become airborne (Green et al, 2005). The personal exposure to airborne fungal spores and their components is strongly linked to allergic diseases and dysfunction of respiratory system including allergic rhinitis, bronchopulmonary, and hypersensitivity diseases (Koppelman, 2007) pneumonitis and bronchial asthma (Masoli et al, 2004;Bousquet et al, 2008).…”

Section: Airborne Fungal Spores and Allergymentioning

confidence: 99%

Dynamics (seasonal and intra-diurnal) of air-borne fungal spore population of Doha area, Qatar

Fayad

2016

Qatar University Life Science Symposium 2016: Biodiversity, Sustainability and Climate Change, With Perspectives From Qatar

View full text Add to dashboard Cite

Section: Airborne Fungal Spores and Allergymentioning

confidence: 99%

Dynamics (seasonal and intra-diurnal) of air-borne fungal spore population of Doha area, Qatar

Fayad

2016

Qatar University Life Science Symposium 2016: Biodiversity, Sustainability and Climate Change, With Perspectives From Qatar

View full text Add to dashboard Cite

“…Eine Vielzahl möglicherweise relevanter Pilzallergene entzieht sich damit einer spezifischen Sensibilisierungsdiagnostik [23,24].…”

Section: Oberflächen Und Materialienunclassified

Schimmelpilzbelastung in Innenräumen – Befunderhebung, gesundheitliche Bewertung und Maßnahmen

Dott¹,

Drexler²,

Dunkelberg³

et al. 2007

Bundesgesundheitsbl.

View full text Add to dashboard Cite

“…Hyphal fragments have been shown to represent 6-56% of the total fungal particle counts in field samples based on microscopic sample analysis (Li and Kendrick, 1996;Foto et al, 2005;Green et al, 2005). This method is limited typically to particles >1 μm (Green et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Fungal fragments in moldy houses: A field study in homes in New Orleans and Southern Ohio

Reponen

Seo

Grimsley

et al. 2007

Atmospheric Environment

View full text Add to dashboard Cite

Smaller-sized fungal fragments (<1 μm) may contribute to mold-related health effects. Previous laboratory-based studies have shown that the number concentration of fungal fragments can be up to 500 times higher than that of fungal spores, but this has not yet been confirmed in a field study due to lack of suitable methodology. We have recently developed a field-compatible method for the sampling and analysis of airborne fungal fragments. The new methodology was utilized for characterizing fungal fragment exposures in mold-contaminated homes selected in New Orleans, Louisiana and Southern Ohio. Airborne fungal particles were separated into three distinct size fractions: (i) >2.25 μm (spores); (ii) 1.05-2.25 μm (mixture); and (iii) < 1.0 μm (submicrometersized fragments). Samples were collected in five homes in summer and winter and analyzed for (1→3)-β-D-glucan. The total (1→3)-β-D-glucan varied from 0.2 to 16.0 ng m −3 . The ratio of (1→3)-β-D-glucan mass in fragment size fraction to that in spore size fraction (F/S) varied from 0.011 to 2.163. The mass ratio was higher in winter (average = 1.017) than in summer (0.227) coinciding with a lower relative humidity in the winter. Assuming a mass-based F/S-ratio=1 and the spore size = 3 μm, the corresponding number-based F/S-ratio (fragment number/spore number) would be 10 3 and 10 6 , for the fragment sizes of 0.3 and 0.03 μm, respectively. These results indicate that the actual (field) contribution of fungal fragments to the overall exposure may be very high, even much greater than that estimated in our earlier laboratory-based studies.

show abstract

Fungal fragments and undocumented conidia function as new aeroallergen sources

Cited by 132 publications

References 14 publications

Dynamics (seasonal and intra-diurnal) of air-borne fungal spore population of Doha area, Qatar

Dynamics (seasonal and intra-diurnal) of air-borne fungal spore population of Doha area, Qatar

Schimmelpilzbelastung in Innenräumen – Befunderhebung, gesundheitliche Bewertung und Maßnahmen

Fungal fragments in moldy houses: A field study in homes in New Orleans and Southern Ohio

Contact Info

Product

Resources

About