Fungal keratitis after small incision lenticule extraction (SMILE): a case report and review of the literature

Soleimani, Mohammad; Haydar, Ali A.

doi:10.1186/s12348-021-00256-0

Cited by 7 publications

(10 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most common organisms causing post-LASIK infections are Staphylococcus sp., Streptococcus sp., atypical mycobacteria, and fungus. [ 1 2 3 ] The predisposing risk factors are dry eyes, intraoperative epithelial defects, delayed epithelialization, intraoperative contaminations, and the use of topical steroids. Our patient had developed an interface infection with Fusarium sp.…”

Section: Discussionmentioning

confidence: 99%

Post LASIK interface infection: What NEXT?

Venugopal,

Ghorpade,

Ravindran

2023

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Post LASIK interface infection: What NEXT?

Venugopal,

Ghorpade,

Ravindran

2023

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

“…It should be noted that even more sparing interventions do not guarantee absence of complications. Soleimani and Haydar [ 35 ] reported the case of severe unilateral fungal keratitis four days after minimally-invasive SMILE laser vision correction. The generated ulcer did not respond to medicamentous treatment and required penetrated keratoplasty due to perforation.…”

Section: Risk Factorsmentioning

confidence: 99%

“…The generated ulcer did not respond to medicamentous treatment and required penetrated keratoplasty due to perforation. Because of the intrastromal lenticule location and consequently fast spreading of the infection into the deep corneal layers, treatment of infectious keratitis after SMILE turned out to be very difficult [ 35 ].…”

Section: Risk Factorsmentioning

confidence: 99%

Modern Technologies in Diagnosis of Fungal Keratitis (Review)

Sitnova¹,

Svetozarskiy²

2023

Sovrem Tehnol Med

View full text Add to dashboard Cite

Traumas and infectious diseases of the eye play a leading role in the development of corneal blindness responsible for 1.5–2 million cases of vision loss per year. To date, the issue of reducing the incidence of fungal keratitis is acute and needs to be solved worldwide. Trauma as a risk factor for corneal fungal disease is thought to be prevalent in developing countries due to agricultural involvement, while in developed countries the onset of the disease is predisposed by medical advances such as contact vision correction and modern ophthalmic surgery. Thorough analysis of the pathogenesis gives the possibility to describe the action of fungal enzymes, biofilm formation, and the resistance mechanism, which on the one hand explains the aggressive course of the disease and difficulties in its diagnosis, and on the other hand, it encourages searching for new methods of diagnosis and treatment. The non-specific clinical picture of fungal keratitis, the variety and availability of antibiotics nowadays become an obstacle for rapid detection of this pathology. Low public awareness and late visit to an ophthalmologist are also a barrier to successful combating the increasing incidence of fungal keratitis. Belated diagnosis, increasing resistance of fungi to antibiotics, and lack of registered antifungal ophthalmic drugs justify poor treatment efficacy resulting in decreased visual acuity or vision loss . Existing diagnostic methods need systematization and detailed comparison, identifying the advantages and disadvantages of each. This review considers causative agents and their influence on pathogenesis of the disease, describes difficulties of fungal keratitis diagnosis and possible ways of overcoming these problems using new developments, and also outlines further prospects of research in this direction.

show abstract

“…8,9 Although SMILE has excellent outcomes with good predictability, stability, and effectiveness, first performed by Sekundo and Blum in 2008, 10 complications like diffuse lamellar keratitis or IK have also been reported recently. [10][11][12][13] Although the qualitative description of IK after keratorefractive surgery was reviewed in 2016, quantitative and statistical analyses of some parameters were lacking, which were essential to make an early diagnosis and initiate treatment for clinicians. 2 Considering different procedures that were popular in different eras and the characteristics of various surgeries, this study aimed to integrate existing data of IK after different keratorefractive surgeries to analyze the onset time, clinical manifestation, risk factors, microbiological profile, treatment, and outcomes.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Infectious Keratitis After Keratorefractive Surgery: Update and Review of the Literature

Liu

Guo

Wei

et al. 2023

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

View full text Add to dashboard Cite

Objectives:To summarize the clinical manifestations, microbiological profile, treatment, and prognosis of corneal infections after different keratorefractive surgery.Methods:To obtain relevant studies, English-language databases, including PubMed, Ovid Embase, Web of Science, and CLNAHL, were searched from January 1979 to March 2022. The fundamentals of the literature, clinical characteristics, pathogens, and treatments were retrieved for each included article.Results:Eighty-four studies involving 306 infectious eyes were included in this review. Risk factors of potential infection included a history of blepharitis, contact lens usage, and contaminated surgical instruments. The mean onset time was 22.9±38.7 days (range: 1 day to 3 years). The most common organism isolated from infectious keratitis after keratorefractive surgery were Staphylococcus aureus, followed by Mycobacterium and coagulase-negative Staphylococcus. Most of the infections after refractive procedures were sensitive to medical treatment alone, and the ultimate best-corrected visual acuity after medical treatment was as follows: 20/20 or better in 82 cases (37.0%), 20/40 or better in 170 cases (76.5%), and worse than 20/40 in 52 cases (23.5%). Surgical interventions including flap lift, flap amputation, ring removal, and keratoplasty were performed in 120 eyes (44.5%).Conclusions:Most infections after keratorefractive surgery occur within a week, whereas more than half of the cases after laser-assisted in situ keratomileusis happen after about a month. Gram-positive cocci and mycobacterium are the most common isolates. Infections after LASIK, intracorneal ring (ICR) implantation, and small incision lenticule extraction, which primarily occur between the cornea layers, require irrigation of the tunnels or pocket with antibiotics.

show abstract

Fungal keratitis after small incision lenticule extraction (SMILE): a case report and review of the literature

Cited by 7 publications

References 14 publications

Post LASIK interface infection: What NEXT?

Post LASIK interface infection: What NEXT?

Modern Technologies in Diagnosis of Fungal Keratitis (Review)

Infectious Keratitis After Keratorefractive Surgery: Update and Review of the Literature

Contact Info

Product

Resources

About