Fungal panniculitis in renal transplant recipients

Abstract

Panniculitis may result due to various etiologies. In post-transplant immunosuppressed patients infection is the foremost cause of panniculitis. We present 2 cases of fungal panniculitis in renal transplant recipients. The first patient presented with non-tender firm erythematous plaques on the left thigh. Biopsy showed panniculitis with cryptococci. Subsequent investigations revealed the presence of cryptococcal antigens in the blood, urine, and bronchoalveolar lavage fluid. There was no evidence of cryptococcal meningitis. The second patient complained of subcutaneous nodules on the trunk and right thigh. Biopsy of one of the nodules showed panniculitis with histoplasma. This patient had been treated earlier (inadequately) for disseminated histoplasmosis. Both the cases responded well to conventional amphotericin B therapy. Their renal functions remained stable.

Expanding the horizons of histoplasmosis: disseminated histoplasmosis in a renal transplant patient after a trip to Bangladesh

“…Subramanian et al (9) report 18 additional cases diagnosed in India. Review of the literature revealed 51 more cases in India, 3 probable cases, 1 unpublished case mentioned in a review, and 2 cases from personal communications (13–48). Thirteen cases have been diagnosed in the United Kingdom in patients with prior residence on the Indian subcontinent (10), and 1 case was diagnosed in Canada in a patient who had recently traveled to India (49).…”

Cutaneous histoplasmosis in renal transplant recipients

“…Seventeen of these 22 cutaneous histoplasmosis cases, including our patient, occurred in the setting of confirmed disseminated disease . Table displays the demographic data, time from transplantation to clinical presentation, maintenance immunosuppressants, characteristics of cutaneous findings, other organs with confirmed involvement, treatment medications, and final outcome of these 17 cases.…”

Cryptococcal panniculitis and myositis: A diverse manifestation of cryptococcal infection

“…There are only two reported cases of cryptococcal panniculitis in the dermatological published work. 4,5 However, subcutaneous mass-like presentation as seen in our case appears to be very rare.…”