Fungemia Caused by Hansenula anomala: Successful Treatment with Fluconazole.

Abstract

Fungemia, due to Hansenula anomala, developed in an adult patient with small cell lung cancer who received anti-cancer chemotherapy and plasmapheresis for a sensori-motor neuro pathy complication. Treatment with intravenous infusion of fluconazole in addition to the removal of the central venous catheter was successful in treating the fungemia. Pathogenic Hansenula anomala infections are rare, but reports of this infection have been increasing. The use of fluconazole treatment for this infection has not been reported in the literature, and this is the first case of an adult infection of Hansenula anomala in Japan. (Internal Medicine 31: 622-624, 1992)

In Vitro Activity of Seven Systemically Active Antifungal Agents against a Large Global Collection of RareCandidaSpecies as Determined by CLSI Broth Microdilution Methods

“…Data on the antifungal susceptibility of C. pelliculosa (P. anomala) are scarce (2,7,22,33,67). Amphotericin B remains the drug of choice for C. pelliculosa infections due to its in vitro and in vivo activity (Table 2) (29,47).…”

Detection of Pathogenic Yeasts from Processed Fresh Edible Sea Urchins Sold in a Fish Market

“…P. anomala causes fungemia 11 13 . Patients receiving fluconazole treatment for P. anomala show good clinical outcomes 14 , but treatment failures may occur in cases of breakthrough fungemias in immunocompromised patients receiving prophylaxis with fluconazole 15 . In addition, P. anomala has shown low susceptibility to itraconazole 16 .…”

Wickerhamomyces anomalus blood stream infection in a term newborn with pneumonia

“…W. anomalus is a yeast frequently found in various fruits, tree exudates, soil, vegetables and other organic compounds 9 . It has occasionally been reported as a causative agent of fungaemia in both immunocompetent and immunocompromised patients, including those with AIDS [10][11][12][13][14][15][16][17][18][19][20] . W. anomalus has also been reported as a causative agent of nosocomial cerebral ventriculitis in low-birth-weight neonates, endocarditis in an intravenous drug abuser and urinary tract infection in a renal transplant recipient 18,[21][22][23] .…”