Furfural and Hydroxymethylfurfural inhibition of growth and photosynthesis in<i>Spirulina</i>

Yu, Shukun; Försberg, Åke; Kral, Keith; Pedersén, Marianne

doi:10.1080/00071619000650131

Cited by 11 publications

(6 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Phenolic compounds can be stimulatory or inhibitory for microalgae, but the final effect depends strictly on phenolic structure and concentration, as well as on microalgae strains used [93][94][95]. Furans show inhibitory activity toward microalgae [102,103], but this effect has been scarcely investigated. Furans originate from sugars during lignocellulose treatment and it seems necessary to either maintain furan concentration below the inhibitory threshold or apply a pre-adaptation step to increase the resistance of microalgae strains to furans in the cultivation medium enriched with lignocellulose derived compounds [103].…”

Section: Discussionmentioning

confidence: 99%

“…Inhibition of photosynthesis was detected and shown by the decrease in oxygen production. Additionally, it was concluded that furans could interfere in metabolic processes and cause lysis of Spirulina cells [102]. Recently, it has been reported that furfural up to 0.6 g/L can cause 30% biomass reduction during mixotrophic acetate-based cultivation of Chlamydomonas reinhardtii [103].…”

Section: Furansmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Lignocellulose Related Compounds on Microalgae Growth and Product Biosynthesis: A Review

et al. 2014

View full text Add to dashboard Cite

Microalgae contain valuable compounds that can be harnessed for industrial applications. Lignocellulose biomass is a plant material containing in abundance organic substances such as carbohydrates, phenolics, organic acids and other secondary compounds. As growth of microalgae on organic substances was confirmed during heterotrophic and mixotrophic cultivation, lignocellulose derived compounds can become a feedstock to cultivate microalgae and produce target compounds. In this review, different treatment methods to hydrolyse lignocellulose into organic substrates are presented first. Secondly, the effect of lignocellulosic hydrolysates, organic substances typically present in lignocellulosic hydrolysates, as well as minor co-products, on growth and accumulation of target compounds in microalgae cultures is described. Finally, the possibilities of using lignocellulose hydrolysates as a common feedstock for microalgae cultures are evaluated.Keywords: lignocellulose; hydrolysis; microalgae; cultivation; extraction; bioproducts OPEN ACCESSEnergies 2014, 7 4447 Microalgae: A Source of Valuable CompoundsMicroalgae include several groups of microorganisms that belong to the Prokaryota or Eukaryota, typically found in fresh water or marine systems in single cell forms or in groups. They are capable of performing photosynthesis, producing approximately half of the atmospheric oxygen while using the greenhouse gas carbon dioxide to grow photoautotrophically [1]. Microalgae contain valuable compounds such as lipids, proteins and pigments (Table 1) which have substantial potential for commercial applications. Microalgae cells accumulate lipids which include triacylglycerides (TAGs), polyunsaturated fatty acids (PUFAs) and sterols [2]. These lipids constitute storage materials or membrane structural components in microalgae and can be used for biofuel, food supplement and pharmaceutical production. Indeed, fossil fuels are nowadays still the main source of carbon based fuels, the exploitation of which causes emission of greenhouse CO 2 . Biodiesel production from oil crops is seen as currently the best alternative, but still presents the main drawback of competing with food production for arable land. Therefore, production of biodiesel from TAGs present in microalgae can become an environmentally friendly alternative as microalgae produce oil and fix CO 2 from atmosphere without the necessity of implementing vast arable areas for cultivation [3]. On the other hand, consumption of PUFAs in the human diet can help prevent the development of cardiovascular and mental diseases [4]. Fish are a rich source of PUFAs, but uncontrolled fishing has led to a substantial decrease in the worldwide fish population [5]. Production of PUFAs from microalgae may overcome this problem. On the other hand, sterols from microalgae are important part of the diet for juvenile scallops or prawns in aquaculture hatcheries [6]. Moreover, the high protein content in microalgae makes them a possible fodder for agricultural livestock [7]. In ad...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Furansmentioning

confidence: 99%

Effect of Lignocellulose Related Compounds on Microalgae Growth and Product Biosynthesis: A Review

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Instead, the inhibition is likely to be caused by the presence of organic compounds such as hydroxy methyl furfural (HMF), furfural, phenol or formic acid, produced during the carbonisation of biomass >190 °C [39,44,57,58]. HMF and furfural (~1 mM) can delay the growth of algae, whilst concentrations above 7 mM can completely inhibit algal growth by blocking electron transfer in the photosynthetic electron transport system [14,59]. Although the total organic carbon content in the HTC-AP from the current study was relatively independent of temperature, higher temperatures can increase the conversion of water-soluble intermediates, such as amino acids and sugars, into more toxic secondary products, increasing their inhibitory effect on algae cultivation.…”

Section: Cultivation Of Dunaliella Tertioleta In Htc-apmentioning

confidence: 99%

Hydrothermal carbonisation of anaerobic digestate for hydro-char production and nutrient recovery

Roy

Radu

Wagner

2022

Journal of Environmental Chemical Engineering

View full text Add to dashboard Cite

“…17,36 In the case of activated sludge, values of EC 50 (760 mg L −1 ) for activity have been reported 32. Previous works reported several toxicity mechanisms of furfural on microbial metabolism, including hydroxyl radical damage of DNA, inhibition of glycolytic enzymes and a decrease in NADP availability. [37][38][39] Yu et al 13 described the toxicity of furfural over the photosynthesis of several species of the cyanobacteria Spirulina spp., whereas Modig et al 40 reported inhibition of the Krebs cycle by the enzyme pyruvate dehydrogenase.…”

Section: Effect Of Furfuralmentioning

confidence: 99%

“…11 Furfural also causes significant inhibition during anaerobic digestion 12 and it negatively affects photosynthetic activity. 13 Other potentially toxic organic compounds present in the RPWW are methyl-di-ethanolamine (MDEA) 14 and butanone (also called methyl ethyl ketone or MEK). 15 The anaerobic treatment of a refinery spent sulfidic caustic stream rich in MDEA showed preliminary inhibitory effects.…”

Section: Introductionmentioning

confidence: 99%

Inhibition of the metabolism of mixed cultures of purple phototrophic bacteria by typical refinery and petrochemistry wastewater pollutants

Martín

Puyol

Melero

et al. 2021

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

BACKGROUND: Anaerobic treatments based on purple phototrophic bacteria (PPB) can be a more efficient and less energetically demanding alternative to aerobic biological processes currently used in refinery and petrochemistry wastewater (RPWW) treatment plants. Toxic compounds in the RPWW might compromise PPB metabolism, limiting its feasibility. In this work, seven toxic compounds that are typical components of RPWW [benzene, toluene, ethylbenzene, o-xylene (BTEX), furfural, methyl-di-ethanolamine (MDEA) and butanone] were evaluated as potential inhibitors of the specific activity and growth of PPB. RESULTS: Inhibitory K i parameters of 50% reduction of specific activity or biomass yield were calculated. Most of the BTEX compounds showed initial inhibitory effects on the specific activity, with K i values of 305 ± 9, 151 ± 17 and 84 ± 2 mg L −1 for benzene, toluene and ethylbenzene, respectively. These compounds also caused inhibition of PPB growth (K i of 411 ± 7 and 241 ± 3 mg L −1 , 26% below the control, respectively). By contrast, o-xylene affected neither the activity nor the growth. Furfural inhibited the initial specific activity (K i of 448 ± 24 mg L −1 ), with no effect over the PPB growth. However, MDEA and butanone improved the initial specific activity of PPB (15% and 40% above the control, respectively). However, butanone negatively impacted the growth which decreased to ≤40% below the control. CONCLUSIONS: Calculated inhibition thresholds for the seven toxic compounds were far above the actual concentrations found in the RPWW. Thus, anaerobic treatments based on PPB for the treatment of RPWW would not be limited by the presence of the toxic compounds studied here.

show abstract

Furfural and Hydroxymethylfurfural inhibition of growth and photosynthesis inSpirulina

Cited by 11 publications

References 15 publications

Effect of Lignocellulose Related Compounds on Microalgae Growth and Product Biosynthesis: A Review

Effect of Lignocellulose Related Compounds on Microalgae Growth and Product Biosynthesis: A Review

Hydrothermal carbonisation of anaerobic digestate for hydro-char production and nutrient recovery

Inhibition of the metabolism of mixed cultures of purple phototrophic bacteria by typical refinery and petrochemistry wastewater pollutants

Contact Info

Product

Resources

About