Further Experience With the Roentgen Diagnosis of Idiopathic Steatorrhea

Kantor, John L.

doi:10.1001/archinte.1940.00190110117008

Cited by 9 publications

(2 citation statements)

References 13 publications

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“…The loss of small bowel folds in patients with CD was first recongised in the 1930s. The “moulage sign” by Kantor described the featureless appearance of the dilated jejunal loops following the introduction of contrast media, resembling a tube into which wax has been poured ( 6 ). Decades later, the advent of endoscopy allowed the direct visualisation of the small bowel mucosa and the acquisition of duodenal biopsies to confirm the diagnosis of CD.…”

Section: Discussionmentioning

confidence: 99%

Role of endoscopy in the diagnosis of coeliac disease: a narrative review

Shiha,

Yusuf,

Sanders

2024

Transl Gastroenterol Hepatol

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Background and Objective Coeliac disease (CD) is a common autoimmune disorder triggered by gluten consumption in genetically predisposed individuals. CD is characterised by chronic inflammation in the small bowel mucosa with an influx of lymphocytes, followed by crypt hyperplasia and villous atrophy. The gold standard test to diagnose CD is endoscopy with duodenal biopsies. However, variations in practice between endoscopists can lead to missed diagnoses. This review aims to discuss the role of endoscopy in the diagnosis of CD, highlighting the performance measures of endoscopy in CD and the advancement in endoscopic techniques for the optical diagnosis of villous atrophy. Methods We searched PubMed and Google Scholar from their inception to December 2023 for relevant articles on the role of endoscopy in CD. Two authors reviewed these references, and relevant studies were included in the discussion section of this review. Key Content and Findings We provide an up-to-date assessment of the diagnostic accuracy of endoscopic markers of CD and the performance of enhanced endoscopic imaging to identify villous atrophy during endoscopy. We propose a set of benchmarks for endoscopy in CD and discuss the potential role of artificial intelligence (AI) in the endoscopic diagnosis of CD. Conclusions Performing high-quality endoscopy and identifying strategies to reduce inter-endoscopist variations may reduce missed diagnoses. Adopting advanced endoscopic techniques and embracing new technologies such as AI could enhance diagnostic accuracy and improve patient care.

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Section: Discussionmentioning

confidence: 99%

Role of endoscopy in the diagnosis of coeliac disease: a narrative review

Shiha,

Yusuf,

Sanders

2024

Transl Gastroenterol Hepatol

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“…Radiology is, of course, of considerable importance. In idiopathic steatorrhcea gastric dilatation and megacolon are often seen and indicate some degree of intestinal atony ( Snell and Camp, 1934;Kantor, 1940), and clumping of the barium in the small intestine (" deficiency pattern ", " moulage sign ") is also a diagnostic appearance. But these radiological signs may also be present in symptomatic cases, and one must in addition look for filling defects, internal fistula; and other abnormal appearances which may point to the true diagnosis.…”

Section: Mean Of 18 Normal5mentioning

confidence: 99%