Future directions in percutaneous vertebroplasty

Masala, Salvatore; Massari, Francesco; Fiori, Roberto; Mammucari, Matteo; Bartolucci, Dario Alberto; Simonetti, Giovanni

doi:10.1007/s11547-009-0418-2

Cited by 9 publications

(9 citation statements)

References 19 publications

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“…The vertebral compression fracture occurs when the spine bears the body weight and consequently increases pain and even causes neurological symptoms [161718]. …”

Section: Discussionmentioning

confidence: 99%

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Elnoamany

2016

Asian Spine J

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Study DesignProspective cohort study.PurposeTo evaluate the clinical and radiological results of percutaneous selective vertebroplasty (PSV) as first-line treatment options in the setting of well-confined spinal metastases.Overview of LiteratureRecent technological advances combined with innovative interventional techniques enable an alternative less invasive treatment option for many patients with malignant vertebral body infiltration. Percutaneous vertebral augmentation procedures offer less invasive but effective pain relief to many patients with symptomatic spinal metastatic disease.MethodsEleven patients with 21 well-confined metastatic vertebral lesions that had been treated with PSV were included. Pain was evaluated one week, one month, 3 months and 6 months post-procedure using a 10-point visual analogue scale (VAS). A statistical analysis including repeated measures analysis of variance test was used to collectively indicate the presence of any significant differences between different time sequences. Medication usage and range of mobility were also evaluated.ResultsThe 11 patients had an average age of 42 years and 54.5% were male. Highly significant improvements in VAS scores at rest and with activity (p<0.001) were evident. There was a significant decrease in rate of medication consumption post-procedure (p<0.05).ConclusionsPSV can be used successfully as the first-line treatment for well-confined metastatic vertebral lesions. It is also an effective method to decrease pain, increase mobility, and decrease narcotic administration in such patients.

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“…The vertebral compression fracture occurs when the spine bears the body weight and consequently increases pain and even causes neurological symptoms [161718]. …”

Section: Discussionmentioning

confidence: 99%

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Elnoamany

2016

Asian Spine J

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“…Since the destruction of metastatic tumors is mostly osteolytic, it often results in bone defects. The vertebral compression fracture occurs when the spine bears the body weight and consequently increases pain and even causes neurological symptoms (5,6,19). The injection of bone cement can strengthen the vertebral structure and restore the height, proof pressure and intensity of vertebral bodies.…”

Section: Discussionmentioning

confidence: 99%

“…Radiotherapy weakens the bone remodeling ability and increases the risk of vertebral collapse and nerve compression (4)(5)(6). By contrast, surgery is more suitable for patients with an oppressed spinal cord, but this causes more trauma and has a high incidence of complications; in particular, corpectomy is not suitable for patients with multiple vertebral metastases.…”

Section: Introductionmentioning

confidence: 99%

Application of percutaneous vertebroplasty in the treatment of multiple thoracic metastases

2015

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Abstract. The present study aimed to explore the clinical implications of percutaneous vertebroplasty (PVP) in the treatment of multiple thoracic metastases. A total of 104 involved vertebrae of 28 patients with multiple thoracic metastases underwent PVP and the injection of bone cement. The pain relief rate and activity of daily life were assessed, and the morphological changes of the involved vertebral bodies and the invasiveness of the intraspinal tumor were also observed at 1 week, and 3, 6 and 12 months post-surgery, respectively. The pain relief rate increased at each time-point following PVP. The quality of life scores were also significantly higher than the pre-operative scores. After 12 months of follow-up, the post-operative heights of the anterior border, center and posterior border of the vertebral bodies were not noted to be statistically different from those prior to PVP (P>0.05). The present study concluded that PVP has a good analgesic effect on multiple thoracic metastases. PVP not only improves the quality of life of patients significantly, but also prevents further vertebral collapse and the invasiveness of intraspinal tumors, avoiding the nerve dysfunction caused by spinal cord compression.

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“…Percutaneous vertebroplasty is a procedure in which bone cement is injected into vertebrae affected by a compression fracture, osteoporosis or myeloma 1 . During the injection, the cement flow is monitored using fluoroscopy to assess the absence of cement leaks, which may lead to severe complications.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Operator Radioprotection Using a New Injection Device during Vertebroplasty

Nguyen-Kim¹,

Fargeot

Beaussier

et al. 2013

Interv Neuroradiol

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This study aimed to evaluate the protection granted by a simple device (X'TENS®, Thiebaud, France) and to provide operators with information on the performance of this new device, which has not yet been assessed. Our assumption is that this device efficiently reduces the radiation dose to the operator. In a prospective clinical study, the radiation dose the operator's hand receives has been assessed using a specific sensor (UNFOR Instrument). Each patient included in the study was to receive at least two injections of cement during the procedure. Exposure was measured with and without the range extender. The data collected were then processed using a Wilcoxon matched pairs test. During 14 interventions, 20 vertebrae were treated with both procedures. Eleven women and three men were included. Seven patients underwent vertebroplasty for metastatic lesions and seven for osteoporotic lesions, bone fractures or vertebral compressions. The average injection time was 1.35 minutes with the device and 1.20 without (p=0.75). The dose to the hand per ml injected was 111.37 vs. 166.91 (p<0.05). Theoretically, the protection granted by the range extender depends on the length of the device. Our results are consistent with the inverse-square law. However, the variations in our results indicate that a proper and rigorous use is mandatory for the device to be effective. Given that radioprotection during fluoroscopy procedures is a frequently raised issue, the need for information for a safer practice increases likewise.

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Future directions in percutaneous vertebroplasty

Cited by 9 publications

References 19 publications

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Application of percutaneous vertebroplasty in the treatment of multiple thoracic metastases

Evaluation of Operator Radioprotection Using a New Injection Device during Vertebroplasty

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