Future of biobanks – bigger, longer, and more dimensional

Polašek, Ozren

doi:10.3325/cmj.2013.54.496

Cited by 24 publications

(18 citation statements)

References 29 publications

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“…This cross-sectional study was performed within the “10,001 Dalmatians” cohort study (25,26). “10,001 Dalmatians” study was initiated in 1999, and has been investigating the health of isolated island communities ever since (27).…”

Section: Methodsmentioning

confidence: 99%

Mediterranean diet in the southern Croatia – does it still exist?

et al. 2016

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AimTo assess the adherence to the Mediterranean diet in the population of Dalmatia in southern Croatia.MethodsA cross-sectional study was performed within the 10 001 Dalmatians cohort, encompassing 2768 participants from Korčula and Vis islands and the City of Split, who were recruited during 2011-2014. Using the data obtained from food frequency questionnaire we calculated the Mediterranean Diet Serving Score (MDSS). Multivariate logistic regression was used to identify the characteristics associated with the adherence to the Mediterranean diet, with age, sex, place of residence, education attainment, smoking, and physical activity as covariates.ResultsThe median MDSS score was 11 out of 24 points (interquartile range 8-13), with the highest score recorded on the island of Vis. Participants reported a dietary pattern that had high compliance with the Mediterranean diet guidelines for consumption of cereals (87% met the criteria), potatoes (73%), olive oil (69%), and fish (61%), moderate for consumption of fruit (54%) and vegetables (31%), and low for consumption of nuts (6%). Overall, only 23% of the participants were classified as being adherent to the Mediterranean diet, with a particularly low percentage among younger participants (12%) compared to the older ones (34%). Men were less likely to show good adherence (odds ratio 0.52, 95% confidence interval 0.42-0.65).ConclusionThis study revealed rather poor compliance with the current recommendations on the Mediterranean diet composition in the population of Dalmatia. Public health intervention is especially needed in younger age groups and in men, who show the greatest departure from traditional Mediterranean diet and lifestyle.

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Section: Methodsmentioning

confidence: 99%

Mediterranean diet in the southern Croatia – does it still exist?

et al. 2016

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“…All controls were apparently healthy subjects with no record of addiction, risky behaviors or detected HCV infection (Polašek, 2013; Rudan et al, 2009). …”

Section: Methodsmentioning

confidence: 99%

The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia

Bogdanović

Marinović-Terzić

Kuret

et al. 2016

PeerJ

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BackgroundSeveral genes and their single nucleotide polymorphisms (SNPs) are associated with either spontaneous resolution of hepatitis C infection or better treatment-induced viral clearance. We tested a cohort of intravenous drug users (IVDU) diagnosed with chronic hepatitis C virus (HCV) for treatment response and its association with the SNPs in the interleukin-6 (rs1800795-IL6) and the interleukin-28B (rs12979860-IL28B) genes.MethodsThe study included 110 Croatian IVDU positive for anti-HCV antibody. Genotyping was performed by polymerase chain reaction (PCR) based approach. Patients were treated by standard pegylated-interferon/ribavirin and followed throughout a period of four years, during which sustained virological response (SVR) was determined. All data were analysed with statistical package SPSS 19.0 (IBM Corp, Armonk, NY, USA) and PLINK v1.07 software.ResultsPatients showed a significantly better response to treatment according to the number of copies of the C allele carried at rs1800795-IL6 (P = 0.034). All but one of the patients with CC genotype achieved SVR (93%), whereas the response rate of patients with GG genotype was 64%. The association of rs1800795-IL6 with SVR status remained significant after further adjustment for patients’ age, fibrosis staging, and viral genotype (OR 2.15, 95% CI 1.16–4.68, P = 0.019). Distributions of allele frequencies at the locus rs12979860-IL28B among the study cohort and the underlying general population were suggestive of a protective effect of CC genotype in acquiring chronic hepatitis C in the Croatian IVDU population.DiscussionThe rs1800795-IL6 polymorphism is associated with positive response to treatment in IVDU patients positive for HCV infection. A protective role of rs12979860-IL28B CC genotype in acquiring chronic hepatitis C is suggested for Croatian IVDU population.

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“…Біобанки сьогодні -це новий напрям, що розвивається як самостійна область досліджень із багатьма специфічними компонентами та вимагає спеціалізованих кадрів. Біобанки є репортерами біо-логічних образів та асоційованої з ними інформації для ведення наукової роботи в рамках крупномасш-табних, мультидисциплінарних і мультицентрових дослідницьких проектів [10,21].…”

Section: медична інформатика та інженеріяunclassified

Проблеми Зберігання Медичної Та Біологічної Інформації

Petrov¹,

Мінцер²,

Kryuchyn³

et al. 2018

MIE

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Представлено аналіз використання медичної та біологічної інформації в інформаційно-аналітичних системах. На-ведені дані свідчать про швидке зростання представленої у цифровому вигляді такої інформації, показана важли-вість і необхідність забезпечення її довготермінового зберігання. Представлена інформація про носії інформації, що можуть забезпечити надійне та довготермінове зберігання медичної та біологічної інформації. Особливу увагу приділено аналізу характеристик перспективних типів оптичних носіїв для довготермінового зберігання інформації.Ключові слова: медична та біологічна інформація, довготермінове зберігання даних, молекулярно-генетичнi дані, міграція даних, персоніфікована медицина. The analysis of the use of medical and biological information in information-analytical systems is presented, the given data testify to the rapid growth of such information presented in digital form, the importance and necessity of its longterm storage is shown. Information about media carriers that can provide reliable and long-term storage of medical and biological information is presented. Particular attention is paid to the analysis of the characteristics of promising types of optical media for long-term storage of information. PROBLEMS OF STORAGE OF MEDICAL AND BIOLOGICAL INFORMATION

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Future of biobanks – bigger, longer, and more dimensional

Cited by 24 publications

References 29 publications

Mediterranean diet in the southern Croatia – does it still exist?

Mediterranean diet in the southern Croatia – does it still exist?

The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia

Проблеми Зберігання Медичної Та Біологічної Інформації

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